Michael: tweak

2014-01-23T17:35:57Z

tweak

← Older revision		Revision as of 17:35, 23 January 2014
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	*[http://www.tumorlibrary.com/case/detail.jsp?image_id=2462 SS (tumorlibrary.com)].		*[http://www.tumorlibrary.com/case/detail.jsp?image_id=2462 SS (tumorlibrary.com)].

	===Microscopic===		==Microscopic==
	Comes in three (histologic) flavours:<ref name=Ref_WMSP627>{{Ref WMSP\|627}}</ref><ref>{{cite journal \|author=Schaal CH, Navarro FC, Moraes Neto FA \|title=Primary renal sarcoma with morphologic and immunohistochemical aspects compatible with synovial sarcoma \|journal=Int Braz J Urol \|volume=30 \|issue=3 \|pages=210–3 \|year=2004 \|pmid=15689250 \|doi= \|url=http://www.brazjurol.com.br/may_june_2004/Schaal_ing_210_213.htm}}</ref>		Comes in three (histologic) flavours:<ref name=Ref_WMSP627>{{Ref WMSP\|627}}</ref><ref>{{cite journal \|author=Schaal CH, Navarro FC, Moraes Neto FA \|title=Primary renal sarcoma with morphologic and immunohistochemical aspects compatible with synovial sarcoma \|journal=Int Braz J Urol \|volume=30 \|issue=3 \|pages=210–3 \|year=2004 \|pmid=15689250 \|doi= \|url=http://www.brazjurol.com.br/may_june_2004/Schaal_ing_210_213.htm}}</ref>
	#Spindle cell sarcoma with features of hemangiopericytoma, i.e. [[staghorn vessels]].		#Spindle cell sarcoma with features of hemangiopericytoma, i.e. [[staghorn vessels]].
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	**Can be difficult.		**Can be difficult.

	====Images====		===Images===
	<gallery>		<gallery>
	Image:Monophasic_synovial_sarcoma_-_intermed_mag.jpg \| Monophasic synovial sarcoma with staghorn vessels - intermed. mag. (WC/Nephron)		Image:Monophasic_synovial_sarcoma_-_intermed_mag.jpg \| Monophasic synovial sarcoma with staghorn vessels - intermed. mag. (WC/Nephron)
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	*[http://radiographics.rsna.org/content/26/5/1543.long Monophasic SS (radiographics.rsna.org)].		*[http://radiographics.rsna.org/content/26/5/1543.long Monophasic SS (radiographics.rsna.org)].

	===IHC===		==IHC==
	Features:<ref name=Ref_WMSP627>{{Ref WMSP\|627}}</ref>		Features:<ref name=Ref_WMSP627>{{Ref WMSP\|627}}</ref>
	*Vimentin +ve.		*Vimentin +ve.
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	*PGP in ''PGP9.5'' = protein gene product.<ref name=pmid6343558>{{Cite journal \| last1 = Doran \| first1 = JF. \| last2 = Jackson \| first2 = P. \| last3 = Kynoch \| first3 = PA. \| last4 = Thompson \| first4 = RJ. \| title = Isolation of PGP 9.5, a new human neurone-specific protein detected by high-resolution two-dimensional electrophoresis. \| journal = J Neurochem \| volume = 40 \| issue = 6 \| pages = 1542-7 \| month = Jun \| year = 1983 \| doi = \| PMID = 6343558 }}</ref>		*PGP in ''PGP9.5'' = protein gene product.<ref name=pmid6343558>{{Cite journal \| last1 = Doran \| first1 = JF. \| last2 = Jackson \| first2 = P. \| last3 = Kynoch \| first3 = PA. \| last4 = Thompson \| first4 = RJ. \| title = Isolation of PGP 9.5, a new human neurone-specific protein detected by high-resolution two-dimensional electrophoresis. \| journal = J Neurochem \| volume = 40 \| issue = 6 \| pages = 1542-7 \| month = Jun \| year = 1983 \| doi = \| PMID = 6343558 }}</ref>

	===EM===		==EM==
	Features:<ref name=pmid9930576>{{Cite journal \| last1 = Fisher \| first1 = C. \| title = Synovial sarcoma. \| journal = Ann Diagn Pathol \| volume = 2 \| issue = 6 \| pages = 401-21 \| month = Dec \| year = 1998 \| doi = \| PMID = 9930576 }}</ref>		Features:<ref name=pmid9930576>{{Cite journal \| last1 = Fisher \| first1 = C. \| title = Synovial sarcoma. \| journal = Ann Diagn Pathol \| volume = 2 \| issue = 6 \| pages = 401-21 \| month = Dec \| year = 1998 \| doi = \| PMID = 9930576 }}</ref>
	*Biphasic tumour have biphasic ultrastructural features (unlike spindle cell carcinoma and [[epithelioid sarcoma]]).		*Biphasic tumour have biphasic ultrastructural features (unlike spindle cell carcinoma and [[epithelioid sarcoma]]).
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	**No intermediate filaments, no myofilaments.		**No intermediate filaments, no myofilaments.

	===Molecular pathology===		==Molecular pathology==
	Associated [[translocation]]:		Associated [[translocation]]:
	*t(X;18)(p11.2;q11.2).<ref>URL: [http://www.ncbi.nlm.nih.gov/omim/300813 http://www.ncbi.nlm.nih.gov/omim/300813]. Accessed on: 30 May 2010.</ref>		*t(X;18)(p11.2;q11.2).<ref>URL: [http://www.ncbi.nlm.nih.gov/omim/300813 http://www.ncbi.nlm.nih.gov/omim/300813]. Accessed on: 30 May 2010.</ref>

Michael: more

2013-09-23T04:58:54Z

← Older revision		Revision as of 04:58, 23 September 2013
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	[[Category:Diagnosis]]		[[Category:Diagnosis]]
			[[Category:Soft tissue lesions]]

Michael at 04:57, 23 September 2013

2013-09-23T04:57:49Z

← Older revision		Revision as of 04:57, 23 September 2013
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	\| Width =		\| Width =
	\| Caption = Monophasic synovial sarcoma. [[H&E stain]].		\| Caption = Monophasic synovial sarcoma. [[H&E stain]].
	\| Micro = one of the following (1) spindle cell sarcoma with features of hemangiopericytoma, i.e. [[staghorn vessels]]; (2) biphasic synovial sarcoma (spindle cells with features of hemangiopericytoma, epitheliod glands or nests); (3) primitive round cell type		\| Micro = one of the following: (1) spindle cell sarcoma with features of [[hemangiopericytoma]], i.e. [[staghorn vessels]]; (2) biphasic synovial sarcoma (spindle cells with features of hemangiopericytoma, epitheliod glands or nests); (3) primitive round cell type
	\| Subtypes =		\| Subtypes =
	\| LMDDx = [[MPNST]], [[fibrosarcoma]], [[small round cell tumours]]		\| LMDDx = [[MPNST]], [[hemangiopericytoma]], [[fibrosarcoma]], [[small round cell tumours]], carcinoma
	\| Stains =		\| Stains =
	\| IHC = Vimentin +ve, EMA +ve, BCL2 +ve, CD99 +ve.		\| IHC = Vimentin +ve, EMA +ve, BCL2 +ve, CD99 +ve.

Michael: split-out

2013-09-23T04:55:42Z

split-out

Show changes

Michael: +cat.

2011-10-20T04:41:12Z

+cat.

← Older revision		Revision as of 04:41, 20 October 2011
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	#redirect [[Soft_tissue_lesions#Synovial sarcoma]]		#redirect [[Soft_tissue_lesions#Synovial sarcoma]]

			[[Category:Diagnosis]]

Michael: redirect for now

2011-01-19T03:35:58Z

redirect for now

New page

#redirect [[Soft_tissue_lesions#Synovial sarcoma]]

Synovial sarcoma - Revision history

Michael: tweak

Michael: more

Michael at 04:57, 23 September 2013

Michael: split-out

Michael: +cat.

Michael: redirect for now