Temozolomide - Revision history

Michael at 15:04, 17 May 2017

2017-05-17T15:04:39Z

← Older revision		Revision as of 15:04, 17 May 2017
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	<!--- ==See also==		<!--- ==See also==
	*[[Dacarbazine]]. --->		*[[Dacarbazine]]. --->

			==See also==
			*[[O-6-methylguanine-DNA methyltransferase]].

	==References==		==References==

Jensflorian: wikify

2017-03-23T11:22:05Z

wikify

← Older revision		Revision as of 11:22, 23 March 2017
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	'''Temozolomide''' is an oral alkylating agent used to treat [[glioma]] - especially [[glioblastoma]].<ref>{{Cite journal \| last1 = Stupp \| first1 = R. \| last2 = Hegi \| first2 = ME. \| last3 = Mason \| first3 = WP. \| last4 = van den Bent \| first4 = MJ. \| last5 = Taphoorn \| first5 = MJ. \| last6 = Janzer \| first6 = RC. \| last7 = Ludwin \| first7 = SK. \| last8 = Allgeier \| first8 = A. \| last9 = Fisher \| first9 = B. \| title = Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. \| journal = Lancet Oncol \| volume = 10 \| issue = 5 \| pages = 459-66 \| month = May \| year = 2009 \| doi = 10.1016/S1470-2045(09)70025-7 \| PMID = 19269895 }}</ref>		'''Temozolomide''' is an oral alkylating agent used to treat [[glioma]] - especially [[glioblastoma]].<ref>{{Cite journal \| last1 = Stupp \| first1 = R. \| last2 = Hegi \| first2 = ME. \| last3 = Mason \| first3 = WP. \| last4 = van den Bent \| first4 = MJ. \| last5 = Taphoorn \| first5 = MJ. \| last6 = Janzer \| first6 = RC. \| last7 = Ludwin \| first7 = SK. \| last8 = Allgeier \| first8 = A. \| last9 = Fisher \| first9 = B. \| title = Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. \| journal = Lancet Oncol \| volume = 10 \| issue = 5 \| pages = 459-66 \| month = May \| year = 2009 \| doi = 10.1016/S1470-2045(09)70025-7 \| PMID = 19269895 }}</ref>
	The therapeutic effect is dependent on the O-6-methylguanine-DNA methyltransferase (MGMT) gene promotor methylation.		The therapeutic effect is dependent on the [[O-6-methylguanine-DNA methyltransferase]] (MGMT) gene promotor methylation.
	<!--- ==See also==		<!--- ==See also==
	*[[Dacarbazine]]. --->		*[[Dacarbazine]]. --->

Michael at 17:14, 30 May 2016

2016-05-30T17:14:29Z

← Older revision		Revision as of 17:14, 30 May 2016
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	[[Category:Clinical]]		[[Category:Clinical]]
	[[Category:Neuropathology]]		[[Category:Neuropathology]]
			[[Category:Drugs]]

Jensflorian: Glioma treatment

2016-05-20T06:47:32Z

Glioma treatment

New page

'''Temozolomide''' is an oral alkylating agent used to treat [[glioma]] - especially [[glioblastoma]].<ref>{{Cite journal | last1 = Stupp | first1 = R. | last2 = Hegi | first2 = ME. | last3 = Mason | first3 = WP. | last4 = van den Bent | first4 = MJ. | last5 = Taphoorn | first5 = MJ. | last6 = Janzer | first6 = RC. | last7 = Ludwin | first7 = SK. | last8 = Allgeier | first8 = A. | last9 = Fisher | first9 = B. | title = Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. | journal = Lancet Oncol | volume = 10 | issue = 5 | pages = 459-66 | month = May | year = 2009 | doi = 10.1016/S1470-2045(09)70025-7 | PMID = 19269895 }}</ref>
The therapeutic effect is dependent on the O-6-methylguanine-DNA methyltransferase (MGMT) gene promotor methylation.


==References==
{{Reflist|1}}

[[Category:Clinical]]
[[Category:Neuropathology]]