Michael: split out

2014-10-22T06:29:23Z

split out

← Older revision		Revision as of 06:29, 22 October 2014
Line 1:		Line 1:
	#~~redirect~~ [[~~Ovarian_tumours~~#~~Transitional_cell_carcinoma_of_the_ovary~~]]		'''Transitional cell carcinoma of the ovary''' is a rare malignant [[ovarian tumour]]. It is thought to be related to high-grade [[serous carcinoma of the ovary]].

			==General==
			*Rare.
			*Traditionally in the ''transistional cell tumours'' category - in the surface epithelial group of ovarian tumours.<ref name=Ref_WMSP401>{{Ref WMSP\|401}}</ref>
			*Thought to be related to high-grade [[serous carcinoma of the ovary\|serous carcinoma]].<ref name=pmid23018212>{{Cite journal \| last1 = Ali \| first1 = RH. \| last2 = Seidman \| first2 = JD. \| last3 = Luk \| first3 = M. \| last4 = Kalloger \| first4 = S. \| last5 = Gilks \| first5 = CB. \| title = Transitional cell carcinoma of the ovary is related to high-grade serous carcinoma and is distinct from malignant brenner tumor. \| journal = Int J Gynecol Pathol \| volume = 31 \| issue = 6 \| pages = 499-506 \| month = Nov \| year = 2012 \| doi = 10.1097/PGP.0b013e31824d7445 \| PMID = 23018212 }}</ref>

			==Microscopic==
			Features:<ref name=pmid15087664>{{Cite journal \| last1 = Eichhorn \| first1 = JH. \| last2 = Young \| first2 = RH. \| title = Transitional cell carcinoma of the ovary: a morphologic study of 100 cases with emphasis on differential diagnosis. \| journal = Am J Surg Pathol \| volume = 28 \| issue = 4 \| pages = 453-63 \| month = Apr \| year = 2004 \| doi = \| PMID = 15087664 }}</ref>
			*Cystic spaces:
			**Small - punched-out border - very common.
			**Large.
			*Papillae, usu. large, blunt.
			**Occasionally small and filiform.
			*+/-Bizarre giant cells (35%)
			*+/-Gland-like tubules.
			*+/-Squamous differentiation.
			*+/-[[Psammoma bodies]].
			*Cells:
			**Moderate basophilic cytoplasm and little intervening stroma.
			**Marked nuclear pleomorphism.
			**Mitoses - common.

			Notes:
			#Resembles [[urothelial carcinoma]].<ref name=pmid21073751>{{Cite journal \| last1 = Tazi \| first1 = EM. \| last2 = Lalya \| first2 = I. \| last3 = Tazi \| first3 = MF. \| last4 = Ahellal \| first4 = Y. \| last5 = M'rabti \| first5 = H. \| last6 = Errihani \| first6 = H. \| title = Transitional cell carcinoma of the ovary: a rare case and review of literature. \| journal = World J Surg Oncol \| volume = 8 \| issue = \| pages = 98 \| month = \| year = 2010 \| doi = 10.1186/1477-7819-8-98 \| PMID = 21073751 }}</ref>
			#'''No''' Brenner tumour component (benign or malignant) should be present.<ref name=pmid21073751/>

			===Images===
			<gallery>
			Image:Transitional_cell_carcinoma_of_the_ovary_-_very_low_mag.jpg \| TCC - very low mag. (WC)
			Image:Transitional_cell_carcinoma_of_the_ovary_-_low_mag.jpg \| TCC - low mag. (WC)
			Image:Transitional_cell_carcinoma_of_the_ovary_-_intermed_mag.jpg \| TCC - intermed. mag. (WC)
			Image:Transitional_cell_carcinoma_of_the_ovary_-_high_mag.jpg \| TCC - high mag. (WC)
			Image:Transitional_cell_carcinoma_of_the_ovary_-_very_high_mag.jpg \| TCC - very high mag. (WC)
			</gallery>

			==IHC==
			Features:<ref name=pmid21073751>{{Cite journal \| last1 = Tazi \| first1 = EM. \| last2 = Lalya \| first2 = I. \| last3 = Tazi \| first3 = MF. \| last4 = Ahellal \| first4 = Y. \| last5 = M'rabti \| first5 = H. \| last6 = Errihani \| first6 = H. \| title = Transitional cell carcinoma of the ovary: a rare case and review of literature. \| journal = World J Surg Oncol \| volume = 8 \| issue = \| pages = 98 \| month = \| year = 2010 \| doi = 10.1186/1477-7819-8-98 \| PMID = 21073751 }}</ref>
			#Vimentin +ve,
			#CA-125 +ve.
			#WT1 +ve.
			#CK20 -ve.
			#Thrombomodulin -ve.
			#Uroplakin III -ve.

			Notes:
			*1-6 usu. opposite pattern in urothelial cell carcinoma.

			==See also==
			*[[Urothelial carcinoma]].
			*[[Serous carcinoma of the ovary]].
			*[[Ovarian tumours]].

			==References==
			{{Reflist\|2}}

	[[Category:Diagnosis]]		[[Category:Diagnosis]]
			[[Category:Ovarian tumours]]

Michael: +cat.

2011-10-22T19:40:16Z

+cat.

← Older revision		Revision as of 19:40, 22 October 2011
Line 1:		Line 1:
	#redirect [[Ovarian_tumours#Transitional_cell_carcinoma_of_the_ovary]]		#redirect [[Ovarian_tumours#Transitional_cell_carcinoma_of_the_ovary]]

			[[Category:Diagnosis]]

Michael: redirect (proper spelling

2011-09-11T21:22:43Z

redirect (proper spelling

New page

#redirect [[Ovarian_tumours#Transitional_cell_carcinoma_of_the_ovary]]

Transitional cell carcinoma of the ovary - Revision history

Michael: split out

Michael: +cat.

Michael: redirect (proper spelling