Trisomy 21 - Revision history

Michael: mv to 'down syndomre'

2012-05-05T03:35:47Z

mv to 'down syndomre'

← Older revision		Revision as of 03:35, 5 May 2012
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	~~'''Trisomy 21''', also known as '''Down syndrome''', is a common genetic abnormality.~~		#redirect [[Down syndrome]]

	~~==Characteristics==~~
	~~Mnemonic ''CHILD HAS PROBLEM'':<ref>URL: [http://www.valuemd.com/genetics.php http://www.valuemd.com/genetics.php]. Accessed on: 29 May 2011.</ref>~~
	~~#[[congenital heart disease\|'''C'''ongenital heart disease]] / Cataracts.~~
	~~#'''H'''ypothyroidism / Hypotonia.~~
	#'''I'''ncurved 5th digit (clinodactyly)<ref>URL: [http://www.handresearch.com/diagnostics/simian-line-down-syndrome.htm http://www.handresearch.com/diagnostics/simian-line-down-syndrome.htm]. Accessed on: 29 May 2011.</ref> / Increased gap between 1st and 2nd toe.
	~~#[[Leukemia\|'''L'''eukemia]] risk x2 / Lung problem.~~
	~~#'''D'''uodenal atresia / Delayed development.~~
	~~#[[Hirschsprung disease\|'''H'''irschsprung disease]] / Hearing loss.~~
	~~#[[Alzheimer disease\|'''A'''lzheimer disease]] / Alantoaxial instability.~~
	~~#'''S'''hort neck / Squint.~~
	#~~'''P'''almar crease / Protruding~~ [[~~tongue]].~~
	~~#'''R'''ound face / Rolling eye (nystagmus).~~
	~~#'''O'''cciput flat / Oblique eye fissure.~~
	~~#'''B'''rushfield spots / Brachycephaly.~~
	~~#'''L'''ow nasal bridge / Language problems.~~
	~~#'''E'''picanthic fold / Ears folded.~~
	~~#'''M'''ental retardation / Myoclonus.~~

	~~Notes:~~
	*Brushfield spots = white/grey spots in the iris (the "colour part" of the eye).
	**Image: [http://commons.wikimedia.org/wiki/File:Brushfield_eyes_magnified.jpg Brushfield spots (WC)].

	~~==See also==~~
	*[[Trisomy 13]] (Patau syndrome).
	*[[Trisomy 18]] (Edwards syndrome).
	*[[Chromosomal anomalies]].
	*[[Stillbirth]].

	~~==References==~~
	~~{{Reflist\|1}}~~

	~~==External links==~~
	*[http://www.ttuhsc.edu/fostersom/pediatrics/neonatology/documents/presentations/trisomy21.ppt Down syndrome ~~(ttuhsc.edu)].~~

	~~[[Category:Syndromes~~]]

Michael: /* Characteristics */ w

2011-10-08T15:50:34Z

Characteristics: w

← Older revision		Revision as of 15:50, 8 October 2011
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	#[[Alzheimer disease\|'''A'''lzheimer disease]] / Alantoaxial instability.		#[[Alzheimer disease\|'''A'''lzheimer disease]] / Alantoaxial instability.
	#'''S'''hort neck / Squint.		#'''S'''hort neck / Squint.
	#'''P'''almar crease / Protruding tongue.		#'''P'''almar crease / Protruding [[tongue]].
	#'''R'''ound face / Rolling eye (nystagmus).		#'''R'''ound face / Rolling eye (nystagmus).
	#'''O'''cciput flat / Oblique eye fissure.		#'''O'''cciput flat / Oblique eye fissure.

Michael: /* Characteristics */ +brushfield spots

2011-05-29T21:04:56Z

Characteristics: +brushfield spots

← Older revision		Revision as of 21:04, 29 May 2011
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	#'''R'''ound face / Rolling eye (nystagmus).		#'''R'''ound face / Rolling eye (nystagmus).
	#'''O'''cciput flat / Oblique eye fissure.		#'''O'''cciput flat / Oblique eye fissure.
	#'''B'''rushfield ~~spot~~ / Brachycephaly.		#'''B'''rushfield spots / Brachycephaly.
	#'''L'''ow nasal bridge / Language problems.		#'''L'''ow nasal bridge / Language problems.
	#'''E'''picanthic fold / Ears folded.		#'''E'''picanthic fold / Ears folded.
	#'''M'''ental retardation / Myoclonus.		#'''M'''ental retardation / Myoclonus.

			Notes:
			*Brushfield spots = white/grey spots in the iris (the "colour part" of the eye).
			**Image: [http://commons.wikimedia.org/wiki/File:Brushfield_eyes_magnified.jpg Brushfield spots (WC)].

	==See also==		==See also==

Michael: /* Characteristics */

2011-05-29T21:01:03Z

Characteristics

← Older revision		Revision as of 21:01, 29 May 2011
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	==Characteristics==		==Characteristics==
	Mnemonic ''CHILD HAS PROBLEM'':<ref>URL: [http://www.valuemd.com/genetics.php http://www.valuemd.com/genetics.php]. Accessed on: 29 May 2011.</ref>		Mnemonic ''CHILD HAS PROBLEM'':<ref>URL: [http://www.valuemd.com/genetics.php http://www.valuemd.com/genetics.php]. Accessed on: 29 May 2011.</ref>
	*[[congenital heart disease\|'''C'''ongenital heart disease]] / Cataracts.		#[[congenital heart disease\|'''C'''ongenital heart disease]] / Cataracts.
	*Hypotonia ~~/ Hypothyroidism~~.		#'''H'''ypothyroidism / Hypotonia.
	*Incurved 5th digit (clinodactyly)<ref>URL: [http://www.handresearch.com/diagnostics/simian-line-down-syndrome.htm http://www.handresearch.com/diagnostics/simian-line-down-syndrome.htm]. Accessed on: 29 May 2011.</ref> / Increased gap between 1st and 2nd toe.		#'''I'''ncurved 5th digit (clinodactyly)<ref>URL: [http://www.handresearch.com/diagnostics/simian-line-down-syndrome.htm http://www.handresearch.com/diagnostics/simian-line-down-syndrome.htm]. Accessed on: 29 May 2011.</ref> / Increased gap between 1st and 2nd toe.
	*[[Leukemia]] risk x2 / Lung problem.		#[[Leukemia\|'''L'''eukemia]] risk x2 / Lung problem.
	*Duodenal atresia / Delayed development.		#'''D'''uodenal atresia / Delayed development.
	*[[Hirschsprung disease]] / Hearing loss.		#[[Hirschsprung disease\|'''H'''irschsprung disease]] / Hearing loss.
	*[[Alzheimer disease]] / Alantoaxial instability.		#[[Alzheimer disease\|'''A'''lzheimer disease]] / Alantoaxial instability.
	*Squint ~~/ Short neck~~.		#'''S'''hort neck / Squint.
	*Protruding tongue~~/ Palmar crease~~.		#'''P'''almar crease / Protruding tongue.
	*Round face / Rolling eye (nystagmus).		#'''R'''ound face / Rolling eye (nystagmus).
	*Occiput flat / Oblique eye fissure.		#'''O'''cciput flat / Oblique eye fissure.
	*Brushfield spot / Brachycephaly.		#'''B'''rushfield spot / Brachycephaly.
	*Low nasal bridge / Language problems.		#'''L'''ow nasal bridge / Language problems.
	*Epicanthic fold / Ears folded.		#'''E'''picanthic fold / Ears folded.
	*Mental retardation / Myoclonus.		#'''M'''ental retardation / Myoclonus.

	==See also==		==See also==

Michael: tweak a bit more

2011-05-29T20:56:51Z

tweak a bit more

← Older revision		Revision as of 20:56, 29 May 2011
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	*[[congenital heart disease\|'''C'''ongenital heart disease]] / Cataracts.		*[[congenital heart disease\|'''C'''ongenital heart disease]] / Cataracts.
	*Hypotonia / Hypothyroidism.		*Hypotonia / Hypothyroidism.
	*Incurved 5th ~~finger~~ / Increased gap between 1st and 2nd toe.		*Incurved 5th digit (clinodactyly)<ref>URL: [http://www.handresearch.com/diagnostics/simian-line-down-syndrome.htm http://www.handresearch.com/diagnostics/simian-line-down-syndrome.htm]. Accessed on: 29 May 2011.</ref> / Increased gap between 1st and 2nd toe.
	*[[Leukemia]] risk x2 / Lung problem.		*[[Leukemia]] risk x2 / Lung problem.
	*Duodenal atresia / Delayed development.		*Duodenal atresia / Delayed development.
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	==References==		==References==
	{{Reflist\|1}}		{{Reflist\|1}}

			==External links==
			*[http://www.ttuhsc.edu/fostersom/pediatrics/neonatology/documents/presentations/trisomy21.ppt Down syndrome (ttuhsc.edu)].

	[[Category:Syndromes]]		[[Category:Syndromes]]

Michael: /* Characteristics */ tweak

2011-05-29T20:54:25Z

Characteristics: tweak

← Older revision		Revision as of 20:54, 29 May 2011
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	*[[congenital heart disease\|'''C'''ongenital heart disease]] / Cataracts.		*[[congenital heart disease\|'''C'''ongenital heart disease]] / Cataracts.
	*Hypotonia / Hypothyroidism.		*Hypotonia / Hypothyroidism.
	*~~Incure~~ 5th finger / Increased gap between 1st and 2nd toe.		*Incurved 5th finger / Increased gap between 1st and 2nd toe.
	*[[Leukemia]] risk x2 / Lung problem.		*[[Leukemia]] risk x2 / Lung problem.
	*Duodenal atresia / Delayed development.		*Duodenal atresia / Delayed development.
Line 11:		Line 11:
	*[[Alzheimer disease]] / Alantoaxial instability.		*[[Alzheimer disease]] / Alantoaxial instability.
	*Squint / Short neck.		*Squint / Short neck.
	*Protruding tongue/ ~~Palm~~ crease.		*Protruding tongue/ Palmar crease.
	*Round face / Rolling eye (nystagmus).		*Round face / Rolling eye (nystagmus).
	*Occiput flat / Oblique eye fissure.		*Occiput flat / Oblique eye fissure.
	*Brushfield spot / Brachycephaly.		*Brushfield spot / Brachycephaly.
	*Low nasal bridge / Language ~~problem~~.		*Low nasal bridge / Language problems.
	*Epicanthic fold / ~~Ear~~ folded.		*Epicanthic fold / Ears folded.
	*Mental retardation / Myoclonus.		*Mental retardation / Myoclonus.

	==See also==		==See also==

Michael: fix pneumonic

2011-05-29T20:50:23Z

fix pneumonic

← Older revision		Revision as of 20:50, 29 May 2011
Line 2:		Line 2:

	==Characteristics==		==Characteristics==
	Mnemonic ''My CHILD HAS PROBLEM'':<ref>URL: [http://www.valuemd.com/genetics.php http://www.valuemd.com/genetics.php]. Accessed on: 29 May 2011.</ref>		Mnemonic ''CHILD HAS PROBLEM'':<ref>URL: [http://www.valuemd.com/genetics.php http://www.valuemd.com/genetics.php]. Accessed on: 29 May 2011.</ref>
	*[[congenital heart disease\|'''C'''ongenital heart disease]] / Cataracts.		*[[congenital heart disease\|'''C'''ongenital heart disease]] / Cataracts.
	*Hypotonia / Hypothyroidism.		*Hypotonia / Hypothyroidism.

Michael: create

2011-05-29T20:44:21Z

create

New page

'''Trisomy 21''', also known as '''Down syndrome''', is a common genetic abnormality.

==Characteristics==
Mnemonic ''My CHILD HAS PROBLEM'':<ref>URL: [http://www.valuemd.com/genetics.php http://www.valuemd.com/genetics.php]. Accessed on: 29 May 2011.</ref>
*[[congenital heart disease|'''C'''ongenital heart disease]] / Cataracts.
*Hypotonia / Hypothyroidism.
*Incure 5th finger / Increased gap between 1st and 2nd toe.
*[[Leukemia]] risk x2 / Lung problem.
*Duodenal atresia / Delayed development.
*[[Hirschsprung disease]] / Hearing loss.
*[[Alzheimer disease]] / Alantoaxial instability.
*Squint / Short neck.
*Protruding tongue/ Palm crease.
*Round face / Rolling eye (nystagmus).
*Occiput flat / Oblique eye fissure.
*Brushfield spot / Brachycephaly.
*Low nasal bridge / Language problem.
*Epicanthic fold / Ear folded.
*Mental retardation / Myoclonus.

==See also==
*[[Trisomy 13]] (Patau syndrome).
*[[Trisomy 18]] (Edwards syndrome).
*[[Chromosomal anomalies]].
*[[Stillbirth]].

==References==
{{Reflist|1}}

[[Category:Syndromes]]