Trophoblast - Revision history

Michael: /* Syncytiotrophoblasts */

2016-05-21T05:18:26Z

Syncytiotrophoblasts

← Older revision		Revision as of 05:18, 21 May 2016
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	Note:		Note:
	*Syncytiotrophoblasts arise from cytotrophoblasts.<ref name=pmid24595308>{{Cite journal \| last1 = Díaz \| first1 = P. \| last2 = Wood \| first2 = AM. \| last3 = Sibley \| first3 = CP. \| last4 = Greenwood \| first4 = SL. \| title = Intermediate conductance Ca2+-activated K+ channels modulate human placental trophoblast syncytialization. \| journal = PLoS One \| volume = 9 \| issue = 3 \| pages = e90961 \| month = \| year = 2014 \| doi = 10.1371/journal.pone.0090961 \| PMID = 24595308 }}</ref>		*Syncytiotrophoblasts arise from cytotrophoblasts.<ref name=pmid24595308>{{Cite journal \| last1 = Díaz \| first1 = P. \| last2 = Wood \| first2 = AM. \| last3 = Sibley \| first3 = CP. \| last4 = Greenwood \| first4 = SL. \| title = Intermediate conductance Ca2+-activated K+ channels modulate human placental trophoblast syncytialization. \| journal = PLoS One \| volume = 9 \| issue = 3 \| pages = e90961 \| month = \| year = 2014 \| doi = 10.1371/journal.pone.0090961 \| PMID = 24595308 }}</ref>

			====Images====
			<gallery>
			Image: Seminoma with syncytiotrophoblasts -- low mag.jpg \| Syncytiotrophoblasts in seminoma - low mag.
			Image: Seminoma with syncytiotrophoblasts -- intermed mag.jpg \| Syncytiotrophoblasts in seminoma - intermed. mag.
			Image: Seminoma with syncytiotrophoblasts -- high mag.jpg \| Syncytiotrophoblasts in seminoma - high mag.
			Image: Seminoma with syncytiotrophoblasts -- very high mag.jpg \| Syncytiotrophoblasts in seminoma - very high mag.
			</gallery>

	===Cytotrophoblasts===		===Cytotrophoblasts===

Michael at 03:08, 21 August 2015

2015-08-21T03:08:02Z

← Older revision		Revision as of 03:08, 21 August 2015
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	*beta-hCG -ve.		*beta-hCG -ve.
	*Keratin +ve.		*Keratin +ve.
	**CK7 +ve.<ref name=pmid19069710>{{Cite journal \| last1 = Trenkić \| first1 = M. \| last2 = Basić \| first2 = M. \| last3 = Milentijević \| first3 = M. \| last4 = Petrović \| first4 = A. \| last5 = Zivković \| first5 = V. \| last6 = Lazarević \| first6 = V. \| title = Immunohistohemical evidences of pregnancy in uterine curettage tissue by the use of a double immunocytochemical staining technique using cytokeratin 7 and vimentin antibodies. \| journal = Vojnosanit Pregl \| volume = 65 \| issue = 11 \| pages = 810-3 \| month = Nov \| year = 2008 \| doi = \| PMID = 19069710 }}		**[[CK7]] +ve.<ref name=pmid19069710>{{Cite journal \| last1 = Trenkić \| first1 = M. \| last2 = Basić \| first2 = M. \| last3 = Milentijević \| first3 = M. \| last4 = Petrović \| first4 = A. \| last5 = Zivković \| first5 = V. \| last6 = Lazarević \| first6 = V. \| title = Immunohistohemical evidences of pregnancy in uterine curettage tissue by the use of a double immunocytochemical staining technique using cytokeratin 7 and vimentin antibodies. \| journal = Vojnosanit Pregl \| volume = 65 \| issue = 11 \| pages = 810-3 \| month = Nov \| year = 2008 \| doi = \| PMID = 19069710 }}
	</ref>		</ref>
	*[[EMA]] +ve in 2nd & 3rd trimester.		*[[EMA]] +ve in 2nd & 3rd trimester.

Michael: /* Syncytiotrophoblasts */

2015-02-25T19:20:58Z

Syncytiotrophoblasts

← Older revision		Revision as of 19:20, 25 February 2015
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	**Eosinophilic vacuolated cytoplasm (contains hCG).		**Eosinophilic vacuolated cytoplasm (contains hCG).
	**Closest to mom - covers cytotrophoblast.<ref>[http://upload.wikimedia.org/wikipedia/commons/4/45/Gray37.png http://upload.wikimedia.org/wikipedia/commons/4/45/Gray37.png]</ref>		**Closest to mom - covers cytotrophoblast.<ref>[http://upload.wikimedia.org/wikipedia/commons/4/45/Gray37.png http://upload.wikimedia.org/wikipedia/commons/4/45/Gray37.png]</ref>

			Note:
			*Syncytiotrophoblasts arise from cytotrophoblasts.<ref name=pmid24595308>{{Cite journal \| last1 = Díaz \| first1 = P. \| last2 = Wood \| first2 = AM. \| last3 = Sibley \| first3 = CP. \| last4 = Greenwood \| first4 = SL. \| title = Intermediate conductance Ca2+-activated K+ channels modulate human placental trophoblast syncytialization. \| journal = PLoS One \| volume = 9 \| issue = 3 \| pages = e90961 \| month = \| year = 2014 \| doi = 10.1371/journal.pone.0090961 \| PMID = 24595308 }}</ref>

	===Cytotrophoblasts===		===Cytotrophoblasts===

Michael: /* IHC */

2014-06-22T03:14:03Z

IHC

← Older revision		Revision as of 03:14, 22 June 2014
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	**CK7 +ve.<ref name=pmid19069710>{{Cite journal \| last1 = Trenkić \| first1 = M. \| last2 = Basić \| first2 = M. \| last3 = Milentijević \| first3 = M. \| last4 = Petrović \| first4 = A. \| last5 = Zivković \| first5 = V. \| last6 = Lazarević \| first6 = V. \| title = Immunohistohemical evidences of pregnancy in uterine curettage tissue by the use of a double immunocytochemical staining technique using cytokeratin 7 and vimentin antibodies. \| journal = Vojnosanit Pregl \| volume = 65 \| issue = 11 \| pages = 810-3 \| month = Nov \| year = 2008 \| doi = \| PMID = 19069710 }}		**CK7 +ve.<ref name=pmid19069710>{{Cite journal \| last1 = Trenkić \| first1 = M. \| last2 = Basić \| first2 = M. \| last3 = Milentijević \| first3 = M. \| last4 = Petrović \| first4 = A. \| last5 = Zivković \| first5 = V. \| last6 = Lazarević \| first6 = V. \| title = Immunohistohemical evidences of pregnancy in uterine curettage tissue by the use of a double immunocytochemical staining technique using cytokeratin 7 and vimentin antibodies. \| journal = Vojnosanit Pregl \| volume = 65 \| issue = 11 \| pages = 810-3 \| month = Nov \| year = 2008 \| doi = \| PMID = 19069710 }}
	</ref>		</ref>
	*EMA +ve in 2nd & 3rd trimester.		*[[EMA]] +ve in 2nd & 3rd trimester.
	*CD146 +ve.<ref>URL: [http://www.epitomics.com/diagnostics/product/5618 http://www.epitomics.com/diagnostics/product/5618]. Accessed on: 14 August 2011.</ref>		*CD146 +ve.<ref>URL: [http://www.epitomics.com/diagnostics/product/5618 http://www.epitomics.com/diagnostics/product/5618]. Accessed on: 14 August 2011.</ref>

Michael: /* Villi and age - table */

2013-10-30T16:29:39Z

Villi and age - table

← Older revision		Revision as of 16:29, 30 October 2013
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	\| '''Other'''		\| '''Other'''
	\|-		\|-
	\| First trimester (<13 weeks<ref>{{Cite journal \| last1 = Haggerty \| first1 = CL. \| last2 = Seifert \| first2 = ME. \| last3 = Tang \| first3 = G. \| last4 = Olsen \| first4 = J. \| last5 = Bass \| first5 = DC. \| last6 = Karumanchi \| first6 = SA. \| last7 = Ness \| first7 = RB. \| title = Second trimester anti-angiogenic proteins and preeclampsia. \| journal = Pregnancy Hypertens \| volume = 2 \| issue = 2 \| pages = 158-163 \| month = Apr \| year = 2012 \| doi = 10.1016/j.preghy.2012.01.005 \| PMID = 22712058 }}</ref>)		\| First trimester (<13 weeks<ref name=pmid22712058>{{Cite journal \| last1 = Haggerty \| first1 = CL. \| last2 = Seifert \| first2 = ME. \| last3 = Tang \| first3 = G. \| last4 = Olsen \| first4 = J. \| last5 = Bass \| first5 = DC. \| last6 = Karumanchi \| first6 = SA. \| last7 = Ness \| first7 = RB. \| title = Second trimester anti-angiogenic proteins and preeclampsia. \| journal = Pregnancy Hypertens \| volume = 2 \| issue = 2 \| pages = 158-163 \| month = Apr \| year = 2012 \| doi = 10.1016/j.preghy.2012.01.005 \| PMID = 22712058 }}</ref>)
	\| present		\| present
	\| both can be identified		\| both can be identified

Michael: /* Age of villi */

2013-10-30T16:26:04Z

Age of villi

← Older revision		Revision as of 16:26, 30 October 2013
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	==Age of villi==		==Age of villi==
	===Young villi===		===Young villi===
	*~~Do not have~~ [[blood vessel]]s.		*Few [[blood vessel]]s, central location.
	*Few syncytial knots.		*Few syncytial knots.

	===Old villi===		===Old villi===
	*Blood vessels present and at the periphery of ~~villus - contain nucleated (fetal) RBCs~~.		*Blood vessels present and at the periphery of villi.
	*Syncytial knots.		*Syncytial knots.

Michael: /* Age of villi */

2013-10-30T16:25:08Z

Age of villi

← Older revision		Revision as of 16:25, 30 October 2013
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	===Young villi===		===Young villi===
	*Do not have [[blood vessel]]s.		*Do not have [[blood vessel]]s.
	*No syncytial knots.		*Few syncytial knots.

	===Old villi===		===Old villi===

Michael: /* Images */ more images

2013-07-20T10:10:14Z

Images: more images

← Older revision		Revision as of 10:10, 20 July 2013
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	====Images====		====Images====
	<gallery>		<gallery>
	Image:~~Chorionic_villi_~~-~~_intermed_mag~~.jpg \| Chorionic villi - intermed. mag. (WC)		Image: Chorionic villi - low mag.jpg \| Chorionic villi - low mag. (WC)
	Image:~~Chorionic_villi_~~-~~_very_high_mag~~.jpg \| Chorionic villi - very high mag. - image has numerous annotations. (WC)		Image: Chorionic villi - intermed mag.jpg \| Chorionic villi - intermed. mag. (WC)
			Image: Chorionic villi - high mag.jpg \| Chorionic villi - high mag. (WC)
			Image: Chorionic villi - very high mag.jpg \| Chorionic villi - very high mag. - image has numerous annotations. (WC)
	</gallery>		</gallery>
	www:		www:

Michael: /* Images */

2013-07-20T10:08:45Z

Images

← Older revision		Revision as of 10:08, 20 July 2013
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	====Images====		====Images====
	<gallery>		<gallery>
			Image:Intermediate trophoblast - intermed mag.jpg \| IT - intermed. mag. (WC/Nephron)
			Image:Intermediate trophoblast 2 - intermed mag.jpg \| IT - intermed. mag. (WC/Nephron)
	Image:Intermediate_trophoblast_-_high_mag.jpg \| IT - high mag. (WC/Nephron)		Image:Intermediate_trophoblast_-_high_mag.jpg \| IT - high mag. (WC/Nephron)
	Image:Intermediate_trophoblast_-_lmwk_-_high_mag.jpg \| IT - LMWK - high mag. (WC/Nephron)		Image:Intermediate_trophoblast_-_lmwk_-_high_mag.jpg \| IT - LMWK - high mag. (WC/Nephron)

Michael: /* Intermediate trophoblast */ more

2013-07-20T10:07:31Z

Intermediate trophoblast: more

← Older revision		Revision as of 10:07, 20 July 2013
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	**May be multi-nucleated.		**May be multi-nucleated.

	Images:		====Images====
			<gallery>
			Image:Intermediate_trophoblast_-_high_mag.jpg \| IT - high mag. (WC/Nephron)
			Image:Intermediate_trophoblast_-_lmwk_-_high_mag.jpg \| IT - LMWK - high mag. (WC/Nephron)
			</gallery>
			www:
	*[http://pathology2.jhu.edu/trophoblast/introduction.cfm IT - high mag. (jhu.edu)].		*[http://pathology2.jhu.edu/trophoblast/introduction.cfm IT - high mag. (jhu.edu)].
	*[http://commons.wikimedia.org/wiki/File:Intermediate_trophoblast_-_high_mag.jpg IT - high mag. (WC)].
	*[http://commons.wikimedia.org/wiki/File:Intermediate_trophoblast_-_lmwk_-_high_mag.jpg IT - LMWK - high mag. (WC)].

	====IHC====		====IHC====