Usual interstitial pneumonia - Revision history

Michael: /* Alternate */

2022-02-07T22:32:51Z

Alternate

← Older revision		Revision as of 22:32, 7 February 2022
Line 103:		Line 103:
	Right Lower Lobe of Lung, Wedge Resection:		Right Lower Lobe of Lung, Wedge Resection:
	- Usual interstitial pneumonia (UIP) pattern (fibroblast foci, bronchiolization,		- Usual interstitial pneumonia (UIP) pattern (fibroblast foci, bronchiolization,
	extensive fibroelastotic scarring and focal calcification/bone formation), see comment.		extensive fibroelastotic scarring and focal calcification/bone formation), see comment.

	Comment:		Comment:

Michael: /* Sign out */

2022-02-07T22:30:45Z

Sign out

← Older revision		Revision as of 22:30, 7 February 2022
Line 97:		Line 97:
	There are no findings to specifically suggest hypersensitivity. Clinical and radiologic		There are no findings to specifically suggest hypersensitivity. Clinical and radiologic
	correlation is suggested.		correlation is suggested.
			</pre>

			===Alternate===
			<pre>
			Right Lower Lobe of Lung, Wedge Resection:
			- Usual interstitial pneumonia (UIP) pattern (fibroblast foci, bronchiolization,
			extensive fibroelastotic scarring and focal calcification/bone formation), see comment.

			Comment:
			UIP pattern may be idiopathic. It is also be seen in the context of collagen vascular diseases, hypersensitivity reactions, and drugs; these need to be considered in clinical context along with the imaging findings.
	</pre>		</pre>

Michael: /* Sign out */

2016-01-08T15:49:48Z

Sign out

← Older revision		Revision as of 15:49, 8 January 2016
Line 95:		Line 95:

	Comment:		Comment:
	There are no findings to specifically suggest hypersensitivity. Clinical and radiologic correlation is suggested.		There are no findings to specifically suggest hypersensitivity. Clinical and radiologic
			correlation is suggested.
	</pre>		</pre>

Michael: /* Micro */

2016-01-08T15:49:37Z

Micro

← Older revision		Revision as of 15:49, 8 January 2016
Line 101:		Line 101:
	<pre>		<pre>
	Sections show lung parenchyma with:		Sections show lung parenchyma with:
	Fibrosis (severity): present (moderate-to-severe).		Fibrosis (severity; lobar location): present (moderate-to-severe; peripheral predominant).
	Fibrosis - lung field predominance~~, location (peripheral or central)~~: lower lobe > middle lobe > upper lobe~~; peripheral predominant~~.		Fibrosis - lung field predominance: lower lobe > middle lobe > upper lobe.
	Fibroblast foci: present.		Fibroblast foci: present.
	Temporal heterogeneity: present.		Temporal heterogeneity: present.

Michael: /* Sign out */

2016-01-08T15:44:42Z

Sign out

← Older revision		Revision as of 15:44, 8 January 2016
Line 84:		Line 84:

	==Sign out==		==Sign out==
			<pre>
			A. Lung, Right Lower Lobe, Wedge Biopsy:
			- Usual interstitial pneumonia, see comment and microscopic.

			B. Lung, Right Middle Lobe, Wedge Biopsy:
			- Usual interstitial pneumonia, see comment and microscopic.

			C. Lung, Right Upper Lobe, Wedge Biopsy:
			- Usual interstitial pneumonia, see comment and microscopic.

			Comment:
			There are no findings to specifically suggest hypersensitivity. Clinical and radiologic correlation is suggested.
			</pre>

	===Micro===		===Micro===
	<pre>		<pre>
	Sections show lung parenchyma with:		Sections show lung parenchyma with:
	Fibrosis: present ~~- patchy.~~		Fibrosis (severity): present (moderate-to-severe).
	~~Fibrosis severity:~~ moderate-to-severe.		Fibrosis - lung field predominance, location (peripheral or central): lower lobe > middle lobe > upper lobe; peripheral predominant.
	~~Lung~~ field predominance (~~fibrosis~~): lower lobe > middle lobe > upper lobe.
	Fibroblast foci: present.		Fibroblast foci: present.
			Temporal heterogeneity: present.
			Spatial heterogeneity: present.
	Peripheral cyst formation: present.		Peripheral cyst formation: present.
	Inflammation: present - patchy, lymphocyte predominant.		Inflammation: present - patchy, lymphocyte predominant.
	Granulomatous inflammation: absent.		Granulomatous inflammation: absent.
	Blood vessel changes: ~~absent~~.		Blood vessel changes: present, moderate-to-severe.
	Airspace changes: mucous plugs.		Airspace changes: mucous plugs.
	</pre>		</pre>

Michael: /* Micro */

2015-08-26T16:32:08Z

Micro

← Older revision		Revision as of 16:32, 26 August 2015
Line 88:		Line 88:
	<pre>		<pre>
	Sections show lung parenchyma with:		Sections show lung parenchyma with:
	Fibrosis: present, patchy.		Fibrosis: present - patchy.
	Fibrosis severity: moderate-to-severe.		Fibrosis severity: moderate-to-severe.
	Lung field predominance (fibrosis): lower lobe > middle lobe > upper lobe.		Lung field predominance (fibrosis): lower lobe > middle lobe > upper lobe.
	Fibroblast foci: present.		Fibroblast foci: present.
	Peripheral cyst formation: present.		Peripheral cyst formation: present.
	Inflammation: present, patchy, lymphocyte predominant.		Inflammation: present - patchy, lymphocyte predominant.
	Granulomatous inflammation: absent.		Granulomatous inflammation: absent.
	Blood vessel changes: absent.		Blood vessel changes: absent.
			Airspace changes: mucous plugs.
	</pre>		</pre>

Michael: /* Microscopic */

2015-08-26T16:01:09Z

Microscopic

← Older revision		Revision as of 16:01, 26 August 2015
Line 82:		Line 82:
	Image:Fibroblast focus.jpg\|UIP - fibroblast focus - high mag. (WC)		Image:Fibroblast focus.jpg\|UIP - fibroblast focus - high mag. (WC)
	</gallery>		</gallery>

			==Sign out==

			===Micro===
			<pre>
			Sections show lung parenchyma with:
			Fibrosis: present, patchy.
			Fibrosis severity: moderate-to-severe.
			Lung field predominance (fibrosis): lower lobe > middle lobe > upper lobe.
			Fibroblast foci: present.
			Peripheral cyst formation: present.
			Inflammation: present, patchy, lymphocyte predominant.
			Granulomatous inflammation: absent.
			Blood vessel changes: absent.
			</pre>

	==See also==		==See also==

Michael at 19:46, 8 December 2014

2014-12-08T19:46:46Z

← Older revision		Revision as of 19:46, 8 December 2014
Line 27:		Line 27:
	\| Prognosis = usually poor, dependent on amount of fibrosis		\| Prognosis = usually poor, dependent on amount of fibrosis
	\| Other = histologic correlate of ''idiopathic pulmonary fibrosis''		\| Other = histologic correlate of ''idiopathic pulmonary fibrosis''
	\| ClinDDx = [[asbestosis]], [[chronic hypersensitivity pneumonitis]], collagen vascular disease (history missing), chronic drug toxicity (history missing)		\| ClinDDx = [[asbestosis]], [[chronic hypersensitivity pneumonitis]], collagen vascular disease (history missing), chronic drug toxicity (history missing), idiopathic pulmonary fibrosis
	\| Tx = lung transplantation		\| Tx = lung transplantation
	}}		}}

Michael at 19:43, 8 December 2014

2014-12-08T19:43:48Z

← Older revision		Revision as of 19:43, 8 December 2014
Line 31:		Line 31:
	}}		}}
	'''Usual interstitial pneumonia''', abbreviated '''UIP''', is a relatively common pattern in [[diffuse lung disease]]s. Overall, it is an uncommon pathology.		'''Usual interstitial pneumonia''', abbreviated '''UIP''', is a relatively common pattern in [[diffuse lung disease]]s. Overall, it is an uncommon pathology.

			''Idiopathic pulmonary fibrosis'' (abbreviated ''IPF'') redirects here.

	==General==		==General==

Michael: tweak

2014-07-25T07:10:32Z

tweak

← Older revision		Revision as of 07:10, 25 July 2014
Line 30:		Line 30:
	\| Tx = lung transplantation		\| Tx = lung transplantation
	}}		}}
	'''Usual interstitial pneumonia''', abbreviated '''UIP''', is common [[diffuse lung disease]]. Overall, it is uncommon.		'''Usual interstitial pneumonia''', abbreviated '''UIP''', is a relatively common pattern in [[diffuse lung disease]]s. Overall, it is an uncommon pathology.

	==General==		==General==
Line 47:		Line 47:

	Note:		Note:
	*Cysts - have thin walls (think of emphysema, [[lymphangioleiomyomatosis]] et cetera).		*Cysts - have thin walls (think of [[emphysema]], [[lymphangioleiomyomatosis]] et cetera).
	**Cysts may be isolated/not close to a neighbour.		**Cysts may be isolated/not close to a neighbour.
	**Medcyclopaedia defines it as: thin-walled, well-demarcated and >1 cm.<ref>[http://www.medcyclopaedia.com/library/topics/volume_v_1/l/lung_cyst.aspx http://www.medcyclopaedia.com/library/topics/volume_v_1/l/lung_cyst.aspx]</ref>		**Medcyclopaedia defines it as: thin-walled, well-demarcated and >1 cm.<ref>[http://www.medcyclopaedia.com/library/topics/volume_v_1/l/lung_cyst.aspx http://www.medcyclopaedia.com/library/topics/volume_v_1/l/lung_cyst.aspx]</ref>