Vascular thrombus - Revision history

Michael at 13:10, 6 April 2016

2016-04-06T13:10:29Z

← Older revision		Revision as of 13:10, 6 April 2016
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	'''Vascular thrombus''' is an uncommon [[pathology]] specimen that may be from an artery or vein.		'''Vascular thrombus''' is an uncommon [[pathology]] specimen that may be from an artery or vein.

	''Venous thrombus'' and ''arterial thrombus'' redirect here.		''Venous thrombus'' and ''arterial thrombus'' redirect here. ''Pulmonary embolism'' is dealt with separately in the [[pulmonary embolism]] article.
	==General==		==General==
	*Uncommonly comes to [[pathology]].		*Uncommonly comes to [[pathology]].

Michael at 13:09, 6 April 2016

2016-04-06T13:09:31Z

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	\| Syndromes =		\| Syndromes =
	\| Clinicalhx =		\| Clinicalhx =
	\| Signs =		\| Signs = dependent on severity and location
	\| Symptoms =		\| Symptoms =
	\| Prevalence =		\| Prevalence =
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	\| Rads =		\| Rads =
	\| Endoscopy =		\| Endoscopy =
	\| Prognosis = dependent on severity and ~~location~~		\| Prognosis = dependent on severity, location and underlying cause (if present)
	\| Other =		\| Other =
	\| ClinDDx =		\| ClinDDx =

Michael at 13:06, 6 April 2016

2016-04-06T13:06:22Z

← Older revision		Revision as of 13:06, 6 April 2016
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			{{ Infobox diagnosis
			\| Name = {{PAGENAME}}
			\| Image = Laminations_in_a_thrombus_-_high_mag.jpg
			\| Width =
			\| Caption = Thrombus with laminations. [[H&E stain]]. (WC/Nephron)
			\| Synonyms =
			\| Micro = layers consisting of platelets and fibrin - classically alternating with layers of RBCs (known as ''lines of Zahn'')
			\| Subtypes =
			\| LMDDx = tumour embolus, thromboembolus, fat embolism, amniotic fluid embolus, stasis (post-mortem)
			\| Stains =
			\| IHC =
			\| EM =
			\| Molecular =
			\| IF =
			\| Gross =
			\| Grossing =
			\| Staging =
			\| Site = [[blood vessels]]
			\| Assdx = atrial fibrillation, hypercoagulable states (e.g. cancer)
			\| Syndromes =
			\| Clinicalhx =
			\| Signs =
			\| Symptoms =
			\| Prevalence =
			\| Bloodwork = D-dimer +ve
			\| Rads =
			\| Endoscopy =
			\| Prognosis = dependent on severity and location
			\| Other =
			\| ClinDDx =
			\| Tx = clot buster, thrombectomy, anticoagulants
			}}
	'''Vascular thrombus''' is an uncommon [[pathology]] specimen that may be from an artery or vein.		'''Vascular thrombus''' is an uncommon [[pathology]] specimen that may be from an artery or vein.

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	*Endothelial injury.		*Endothelial injury.

			Clinical:
			*D-dimer elevated.<ref name=pmid23784703>{{Cite journal \| last1 = Kleinegris \| first1 = MC. \| last2 = ten Cate \| first2 = H. \| last3 = ten Cate-Hoek \| first3 = AJ. \| title = D-dimer as a marker for cardiovascular and arterial thrombotic events in patients with peripheral arterial disease. A systematic review. \| journal = Thromb Haemost \| volume = 110 \| issue = 2 \| pages = 233-43 \| month = Aug \| year = 2013 \| doi = 10.1160/TH13-01-0032 \| PMID = 23784703 }}</ref>
	==Gross==		==Gross==
	: See ''[[pulmonary embolism]]''.		: See ''[[pulmonary embolism]]''.

Michael: /* References */

2016-04-05T22:05:44Z

References

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	==References==		==References==
	{{Reflist\|1}}		{{Reflist\|1}}

	[[Category:Diagnosis]]		[[Category:Diagnosis]]
	[[Category:Ditzels]]		[[Category:Ditzels]]
			[[Category:Cardiovascular pathology]]

Michael: /* General */

2016-04-05T22:04:27Z

General

← Older revision		Revision as of 22:04, 5 April 2016
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	*Endothelial injury.		*Endothelial injury.

	===Gross===		==Gross==
	: See ''[[pulmonary embolism]]''.		: See ''[[pulmonary embolism]]''.
	Features:		Features:
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	*Laminations.		*Laminations.

	===Microscopic===		==Microscopic==
	Features:		Features:
	*Layers consisting of platelets and fibrin.		*Layers consisting of platelets and fibrin.

Michael: split out

2016-04-05T22:04:11Z

split out

← Older revision		Revision as of 22:04, 5 April 2016
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	~~#redirect~~ [[~~Ditzels#Vascular_thrombus~~]]		'''Vascular thrombus''' is an uncommon [[pathology]] specimen that may be from an artery or vein.

			''Venous thrombus'' and ''arterial thrombus'' redirect here.
			==General==
			*Uncommonly comes to [[pathology]].

			Risk factors - think [[Virchow's triad]]:
			*Stasis, e.g. atrial fibrillation.
			*Hypercoagulable states, e.g. cancer - see ''[[risks factors venous thromboembolism]]''.
			*Endothelial injury.

			===Gross===
			: See ''[[pulmonary embolism]]''.
			Features:
			*Dull appearance.
			*Laminations.

			===Microscopic===
			Features:
			*Layers consisting of platelets and fibrin.
			**Classically alternating with layers of RBCs - known as ''Lines of Zahn''.<ref name=Ref_PBoD8_124>{{Ref PBoD8\|124}}</ref>

			Note:
			*Multiple laminations (layers), in general, suggest that clot was formed in a dynamic environment, i.e. in the context of blood flow.

			DDx:
			*Tumour embolus - malignant cells.
			*Thromboembolus - may require [[clinical history]].
			*[[Fat embolism]].
			*Amniotic fluid embolus - in the context of pregnancy/postpartum.
			*Foreign body.

			===Images===
			<gallery>
			Image:Laminations_in_a_thrombus_-_low_mag.jpg \| Laminated thrombus - low mag. (WC)
			Image:Laminations_in_a_thrombus_-_high_mag.jpg \| Laminated thrombus - high mag. (WC)
			</gallery>
			====www====
			*[http://library.med.utah.edu/WebPath/ATHHTML/ATH031.html Lines of Zahn (utah.edu)].
			*[http://pathhsw5m54.ucsf.edu/case9/image94.html Lines of Zahn (ucsf.edu)].

			==Sign out==
			<pre>
			BLOOD CLOT, LEFT ILIAC ARTERY, THROMBECTOMY:
			- THROMBUS.
			- NEGATIVE FOR MALIGNANCY.
			</pre>

			<pre>
			BLOOD CLOT, LEFT ARM - BRACHIAL ARTERY, THROMBECTOMY/EMBOLECTOMY:
			- THROMBUS.
			- NEGATIVE FOR MALIGNANCY.
			</pre>

			===Micro===
			The sections show layers of red blood cells alternating with fibrin and white blood cells (Lines of Zahn).

			==See also==
			*[[Cardiovascular pathology]].
			*[[Ditzels]].

			==References==
			{{Reflist\|1}}
	[[Category:Diagnosis]]		[[Category:Diagnosis]]
			[[Category:Ditzels]]

Michael: +dx

2012-11-08T23:10:13Z

+dx

← Older revision		Revision as of 23:10, 8 November 2012
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	#redirect [[Ditzels#Vascular_thrombus]]		#redirect [[Ditzels#Vascular_thrombus]]

			[[Category:Diagnosis]]

Michael: redirect

2012-11-08T23:00:51Z

redirect

New page

#redirect [[Ditzels#Vascular_thrombus]]