WT-1 - Revision history

Michael at 06:51, 1 August 2016

2016-08-01T06:51:51Z

← Older revision		Revision as of 06:51, 1 August 2016
Line 12:		Line 12:
	*[[Wilms tumour]].		*[[Wilms tumour]].
	*[[Metanephric adenoma]].<ref name=pmid24083046>{{Cite journal \| last1 = Watanabe \| first1 = S. \| last2 = Naganuma \| first2 = H. \| last3 = Shimizu \| first3 = M. \| last4 = Ota \| first4 = S. \| last5 = Murata \| first5 = S. \| last6 = Nihei \| first6 = N. \| last7 = Matsushima \| first7 = J. \| last8 = Mikami \| first8 = S. \| last9 = Kuroda \| first9 = N. \| title = Adult nephroblastoma with predominant epithelial component: a differential diagnostic candidate of papillary renal cell carcinoma and metanephric adenoma-report of three cases. \| journal = Case Rep Pathol \| volume = 2013 \| issue = \| pages = 675875 \| month = \| year = 2013 \| doi = 10.1155/2013/675875 \| PMID = 24083046 }}</ref>		*[[Metanephric adenoma]].<ref name=pmid24083046>{{Cite journal \| last1 = Watanabe \| first1 = S. \| last2 = Naganuma \| first2 = H. \| last3 = Shimizu \| first3 = M. \| last4 = Ota \| first4 = S. \| last5 = Murata \| first5 = S. \| last6 = Nihei \| first6 = N. \| last7 = Matsushima \| first7 = J. \| last8 = Mikami \| first8 = S. \| last9 = Kuroda \| first9 = N. \| title = Adult nephroblastoma with predominant epithelial component: a differential diagnostic candidate of papillary renal cell carcinoma and metanephric adenoma-report of three cases. \| journal = Case Rep Pathol \| volume = 2013 \| issue = \| pages = 675875 \| month = \| year = 2013 \| doi = 10.1155/2013/675875 \| PMID = 24083046 }}</ref>

			==Usually negative==
			*[[Serous carcinoma of the endometrium]].<ref name=pmid10786803>{{Cite journal \| last1 = Kounelis \| first1 = S. \| last2 = Kapranos \| first2 = N. \| last3 = Kouri \| first3 = E. \| last4 = Coppola \| first4 = D. \| last5 = Papadaki \| first5 = H. \| last6 = Jones \| first6 = MW. \| title = Immunohistochemical profile of endometrial adenocarcinoma: a study of 61 cases and review of the literature. \| journal = Mod Pathol \| volume = 13 \| issue = 4 \| pages = 379-88 \| month = Apr \| year = 2000 \| doi = 10.1038/modpathol.3880062 \| PMID = 10786803 }}</ref>

	==See also==		==See also==

Michael: /* Tumours with positive staining */

2016-06-06T13:51:30Z

Tumours with positive staining

← Older revision		Revision as of 13:51, 6 June 2016
Line 5:		Line 5:
	*[[Astrocytoma]]/[[Glioblastoma]] (cytoplasmic) ~80-90%.<ref name=pmid18466223>{{Cite journal \| last1 = Schittenhelm \| first1 = J. \| last2 = Beschorner \| first2 = R. \| last3 = Simon \| first3 = P. \| last4 = Tabatabai \| first4 = G. \| last5 = Herrmann \| first5 = C. \| last6 = Schlaszus \| first6 = H. \| last7 = Capper \| first7 = D. \| last8 = Weller \| first8 = M. \| last9 = Meyermann \| first9 = R. \| title = Diagnostic value of WT1 in neuroepithelial tumours. \| journal = Neuropathol Appl Neurobiol \| volume = 35 \| issue = 1 \| pages = 69-81 \| month = Feb \| year = 2009 \| doi = 10.1111/j.1365-2990.2008.00957.x \| PMID = 18466223 }}</ref>		*[[Astrocytoma]]/[[Glioblastoma]] (cytoplasmic) ~80-90%.<ref name=pmid18466223>{{Cite journal \| last1 = Schittenhelm \| first1 = J. \| last2 = Beschorner \| first2 = R. \| last3 = Simon \| first3 = P. \| last4 = Tabatabai \| first4 = G. \| last5 = Herrmann \| first5 = C. \| last6 = Schlaszus \| first6 = H. \| last7 = Capper \| first7 = D. \| last8 = Weller \| first8 = M. \| last9 = Meyermann \| first9 = R. \| title = Diagnostic value of WT1 in neuroepithelial tumours. \| journal = Neuropathol Appl Neurobiol \| volume = 35 \| issue = 1 \| pages = 69-81 \| month = Feb \| year = 2009 \| doi = 10.1111/j.1365-2990.2008.00957.x \| PMID = 18466223 }}</ref>
	*[[Malignant mesothelioma]].<ref name=pmid16554731>{{Cite journal \| last1 = Yaziji \| first1 = H. \| last2 = Battifora \| first2 = H. \| last3 = Barry \| first3 = TS. \| last4 = Hwang \| first4 = HC. \| last5 = Bacchi \| first5 = CE. \| last6 = McIntosh \| first6 = MW. \| last7 = Kussick \| first7 = SJ. \| last8 = Gown \| first8 = AM. \| title = Evaluation of 12 antibodies for distinguishing epithelioid mesothelioma from adenocarcinoma: identification of a three-antibody immunohistochemical panel with maximal sensitivity and specificity. \| journal = Mod Pathol \| volume = 19 \| issue = 4 \| pages = 514-23 \| month = Apr \| year = 2006 \| doi = 10.1038/modpathol.3800534 \| PMID = 16554731 }}</ref>		*[[Malignant mesothelioma]].<ref name=pmid16554731>{{Cite journal \| last1 = Yaziji \| first1 = H. \| last2 = Battifora \| first2 = H. \| last3 = Barry \| first3 = TS. \| last4 = Hwang \| first4 = HC. \| last5 = Bacchi \| first5 = CE. \| last6 = McIntosh \| first6 = MW. \| last7 = Kussick \| first7 = SJ. \| last8 = Gown \| first8 = AM. \| title = Evaluation of 12 antibodies for distinguishing epithelioid mesothelioma from adenocarcinoma: identification of a three-antibody immunohistochemical panel with maximal sensitivity and specificity. \| journal = Mod Pathol \| volume = 19 \| issue = 4 \| pages = 514-23 \| month = Apr \| year = 2006 \| doi = 10.1038/modpathol.3800534 \| PMID = 16554731 }}</ref>

			===Gynecologic pathology===
	*[[Serous ovarian carcinoma]].<ref name=pmid14764054>{{Cite journal \| last1 = Al-Hussaini \| first1 = M. \| last2 = Stockman \| first2 = A. \| last3 = Foster \| first3 = H. \| last4 = McCluggage \| first4 = WG. \| title = WT-1 assists in distinguishing ovarian from uterine serous carcinoma and in distinguishing between serous and endometrioid ovarian carcinoma. \| journal = Histopathology \| volume = 44 \| issue = 2 \| pages = 109-15 \| month = Feb \| year = 2004 \| doi = \| PMID = 14764054 }}</ref>		*[[Serous ovarian carcinoma]].<ref name=pmid14764054>{{Cite journal \| last1 = Al-Hussaini \| first1 = M. \| last2 = Stockman \| first2 = A. \| last3 = Foster \| first3 = H. \| last4 = McCluggage \| first4 = WG. \| title = WT-1 assists in distinguishing ovarian from uterine serous carcinoma and in distinguishing between serous and endometrioid ovarian carcinoma. \| journal = Histopathology \| volume = 44 \| issue = 2 \| pages = 109-15 \| month = Feb \| year = 2004 \| doi = \| PMID = 14764054 }}</ref>

			===Kidney pathology===
	*[[Wilms tumour]].		*[[Wilms tumour]].
	*[[Metanephric adenoma]].<ref name=pmid24083046>{{Cite journal \| last1 = Watanabe \| first1 = S. \| last2 = Naganuma \| first2 = H. \| last3 = Shimizu \| first3 = M. \| last4 = Ota \| first4 = S. \| last5 = Murata \| first5 = S. \| last6 = Nihei \| first6 = N. \| last7 = Matsushima \| first7 = J. \| last8 = Mikami \| first8 = S. \| last9 = Kuroda \| first9 = N. \| title = Adult nephroblastoma with predominant epithelial component: a differential diagnostic candidate of papillary renal cell carcinoma and metanephric adenoma-report of three cases. \| journal = Case Rep Pathol \| volume = 2013 \| issue = \| pages = 675875 \| month = \| year = 2013 \| doi = 10.1155/2013/675875 \| PMID = 24083046 }}</ref>		*[[Metanephric adenoma]].<ref name=pmid24083046>{{Cite journal \| last1 = Watanabe \| first1 = S. \| last2 = Naganuma \| first2 = H. \| last3 = Shimizu \| first3 = M. \| last4 = Ota \| first4 = S. \| last5 = Murata \| first5 = S. \| last6 = Nihei \| first6 = N. \| last7 = Matsushima \| first7 = J. \| last8 = Mikami \| first8 = S. \| last9 = Kuroda \| first9 = N. \| title = Adult nephroblastoma with predominant epithelial component: a differential diagnostic candidate of papillary renal cell carcinoma and metanephric adenoma-report of three cases. \| journal = Case Rep Pathol \| volume = 2013 \| issue = \| pages = 675875 \| month = \| year = 2013 \| doi = 10.1155/2013/675875 \| PMID = 24083046 }}</ref>

Michael at 13:45, 6 June 2016

2016-06-06T13:45:40Z

← Older revision		Revision as of 13:45, 6 June 2016
Line 3:		Line 3:

	==Tumours with positive staining==		==Tumours with positive staining==
	*[[Astrocytoma]]/[[Glioblastoma]] (cytoplasmic) ~80-90% <ref>{{Cite journal \| last1 = Schittenhelm \| first1 = J. \| last2 = Beschorner \| first2 = R. \| last3 = Simon \| first3 = P. \| last4 = Tabatabai \| first4 = G. \| last5 = Herrmann \| first5 = C. \| last6 = Schlaszus \| first6 = H. \| last7 = Capper \| first7 = D. \| last8 = Weller \| first8 = M. \| last9 = Meyermann \| first9 = R. \| title = Diagnostic value of WT1 in neuroepithelial tumours. \| journal = Neuropathol Appl Neurobiol \| volume = 35 \| issue = 1 \| pages = 69-81 \| month = Feb \| year = 2009 \| doi = 10.1111/j.1365-2990.2008.00957.x \| PMID = 18466223 }}</ref>		*[[Astrocytoma]]/[[Glioblastoma]] (cytoplasmic) ~80-90%.<ref name=pmid18466223>{{Cite journal \| last1 = Schittenhelm \| first1 = J. \| last2 = Beschorner \| first2 = R. \| last3 = Simon \| first3 = P. \| last4 = Tabatabai \| first4 = G. \| last5 = Herrmann \| first5 = C. \| last6 = Schlaszus \| first6 = H. \| last7 = Capper \| first7 = D. \| last8 = Weller \| first8 = M. \| last9 = Meyermann \| first9 = R. \| title = Diagnostic value of WT1 in neuroepithelial tumours. \| journal = Neuropathol Appl Neurobiol \| volume = 35 \| issue = 1 \| pages = 69-81 \| month = Feb \| year = 2009 \| doi = 10.1111/j.1365-2990.2008.00957.x \| PMID = 18466223 }}</ref>
	*[[~~Mesothelioma~~]]<ref>{{Cite journal \| last1 = Yaziji \| first1 = H. \| last2 = Battifora \| first2 = H. \| last3 = Barry \| first3 = TS. \| last4 = Hwang \| first4 = HC. \| last5 = Bacchi \| first5 = CE. \| last6 = McIntosh \| first6 = MW. \| last7 = Kussick \| first7 = SJ. \| last8 = Gown \| first8 = AM. \| title = Evaluation of 12 antibodies for distinguishing epithelioid mesothelioma from adenocarcinoma: identification of a three-antibody immunohistochemical panel with maximal sensitivity and specificity. \| journal = Mod Pathol \| volume = 19 \| issue = 4 \| pages = 514-23 \| month = Apr \| year = 2006 \| doi = 10.1038/modpathol.3800534 \| PMID = 16554731 }}</ref>		*[[Malignant mesothelioma]].<ref name=pmid16554731>{{Cite journal \| last1 = Yaziji \| first1 = H. \| last2 = Battifora \| first2 = H. \| last3 = Barry \| first3 = TS. \| last4 = Hwang \| first4 = HC. \| last5 = Bacchi \| first5 = CE. \| last6 = McIntosh \| first6 = MW. \| last7 = Kussick \| first7 = SJ. \| last8 = Gown \| first8 = AM. \| title = Evaluation of 12 antibodies for distinguishing epithelioid mesothelioma from adenocarcinoma: identification of a three-antibody immunohistochemical panel with maximal sensitivity and specificity. \| journal = Mod Pathol \| volume = 19 \| issue = 4 \| pages = 514-23 \| month = Apr \| year = 2006 \| doi = 10.1038/modpathol.3800534 \| PMID = 16554731 }}</ref>
	*~~Serous~~ [[ovarian carcinoma]]<ref>{{Cite journal \| last1 = Al-Hussaini \| first1 = M. \| last2 = Stockman \| first2 = A. \| last3 = Foster \| first3 = H. \| last4 = McCluggage \| first4 = WG. \| title = WT-1 assists in distinguishing ovarian from uterine serous carcinoma and in distinguishing between serous and endometrioid ovarian carcinoma. \| journal = Histopathology \| volume = 44 \| issue = 2 \| pages = 109-15 \| month = Feb \| year = 2004 \| doi = \| PMID = 14764054 }}</ref>		*[[Serous ovarian carcinoma]].<ref name=pmid14764054>{{Cite journal \| last1 = Al-Hussaini \| first1 = M. \| last2 = Stockman \| first2 = A. \| last3 = Foster \| first3 = H. \| last4 = McCluggage \| first4 = WG. \| title = WT-1 assists in distinguishing ovarian from uterine serous carcinoma and in distinguishing between serous and endometrioid ovarian carcinoma. \| journal = Histopathology \| volume = 44 \| issue = 2 \| pages = 109-15 \| month = Feb \| year = 2004 \| doi = \| PMID = 14764054 }}</ref>
			*[[Wilms tumour]].
			*[[Metanephric adenoma]].<ref name=pmid24083046>{{Cite journal \| last1 = Watanabe \| first1 = S. \| last2 = Naganuma \| first2 = H. \| last3 = Shimizu \| first3 = M. \| last4 = Ota \| first4 = S. \| last5 = Murata \| first5 = S. \| last6 = Nihei \| first6 = N. \| last7 = Matsushima \| first7 = J. \| last8 = Mikami \| first8 = S. \| last9 = Kuroda \| first9 = N. \| title = Adult nephroblastoma with predominant epithelial component: a differential diagnostic candidate of papillary renal cell carcinoma and metanephric adenoma-report of three cases. \| journal = Case Rep Pathol \| volume = 2013 \| issue = \| pages = 675875 \| month = \| year = 2013 \| doi = 10.1155/2013/675875 \| PMID = 24083046 }}</ref>

	==See also==		==See also==

Jensflorian: cat

2015-10-14T15:08:20Z

cat

← Older revision		Revision as of 15:08, 14 October 2015
Line 17:		Line 17:

	[[Category:Immunohistochemistry]]		[[Category:Immunohistochemistry]]
			[[Category:Neuropathology]]

Jensflorian: nordiq iq

2015-09-22T06:13:12Z

nordiq iq

← Older revision		Revision as of 06:13, 22 September 2015
Line 12:		Line 12:
	==References==		==References==
	{{Reflist\|1}}		{{Reflist\|1}}

			==External links==
			*[http://www.nordiqc.org/Epitopes/WT1/WT1.htm WT-1(nordiqc.org)].

	[[Category:Immunohistochemistry]]		[[Category:Immunohistochemistry]]

Jensflorian: picture added

2015-06-16T12:09:32Z

picture added

← Older revision		Revision as of 12:09, 16 June 2015
Line 1:		Line 1:
			[[File:Wilms_tumor_protein_wt1_immunohistocehmistry_glioblastoma.JPG\|thumb\|right\|250px\|WT-1 staining in [[glioblastoma]].]]
	'''Wilms Tumor Protein 1''', commonly known by the abbreviation '''WT-1''', is a commonly used [[immunostain]] in [[gynecologic pathology]] and [[neuropathology]].		'''Wilms Tumor Protein 1''', commonly known by the abbreviation '''WT-1''', is a commonly used [[immunostain]] in [[gynecologic pathology]] and [[neuropathology]].

Jensflorian: WT-1 as immunohistochemistry marker

2015-06-16T11:58:38Z

WT-1 as immunohistochemistry marker

New page

'''Wilms Tumor Protein 1''', commonly known by the abbreviation '''WT-1''', is a commonly used [[immunostain]] in [[gynecologic pathology]] and [[neuropathology]].

==Tumours with positive staining==
*[[Astrocytoma]]/[[Glioblastoma]] (cytoplasmic) ~80-90% <ref>{{Cite journal | last1 = Schittenhelm | first1 = J. | last2 = Beschorner | first2 = R. | last3 = Simon | first3 = P. | last4 = Tabatabai | first4 = G. | last5 = Herrmann | first5 = C. | last6 = Schlaszus | first6 = H. | last7 = Capper | first7 = D. | last8 = Weller | first8 = M. | last9 = Meyermann | first9 = R. | title = Diagnostic value of WT1 in neuroepithelial tumours. | journal = Neuropathol Appl Neurobiol | volume = 35 | issue = 1 | pages = 69-81 | month = Feb | year = 2009 | doi = 10.1111/j.1365-2990.2008.00957.x | PMID = 18466223 }}</ref>
*[[Mesothelioma]]<ref>{{Cite journal | last1 = Yaziji | first1 = H. | last2 = Battifora | first2 = H. | last3 = Barry | first3 = TS. | last4 = Hwang | first4 = HC. | last5 = Bacchi | first5 = CE. | last6 = McIntosh | first6 = MW. | last7 = Kussick | first7 = SJ. | last8 = Gown | first8 = AM. | title = Evaluation of 12 antibodies for distinguishing epithelioid mesothelioma from adenocarcinoma: identification of a three-antibody immunohistochemical panel with maximal sensitivity and specificity. | journal = Mod Pathol | volume = 19 | issue = 4 | pages = 514-23 | month = Apr | year = 2006 | doi = 10.1038/modpathol.3800534 | PMID = 16554731 }}</ref>
*Serous [[ovarian carcinoma]]<ref>{{Cite journal | last1 = Al-Hussaini | first1 = M. | last2 = Stockman | first2 = A. | last3 = Foster | first3 = H. | last4 = McCluggage | first4 = WG. | title = WT-1 assists in distinguishing ovarian from uterine serous carcinoma and in distinguishing between serous and endometrioid ovarian carcinoma. | journal = Histopathology | volume = 44 | issue = 2 | pages = 109-15 | month = Feb | year = 2004 | doi = | PMID = 14764054 }}</ref>

==See also==
*[[Immunostains]].

==References==
{{Reflist|1}}

[[Category:Immunohistochemistry]]