Difference between revisions of "Scleroderma"
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==Associated pathology== | ==Associated pathology== | ||
*[[Scleroderma panniculitis]]. | *[[Scleroderma panniculitis]]. | ||
*Digit ischemia - may require [[finger amputation]]. | |||
==See also== | ==See also== | ||
Revision as of 17:34, 20 November 2013
Scleroderma is a disease that keeps rheumatologists busy.
General
Clinical:
- Anti-centromere antibody (ACA) +ve.
- Common in limited systemic scleroderma, AKA CREST syndrome.
- Scl-70 (topoisomerase I) +ve.
- Common in diffuse scleroderma.
CREST syndrome:
- Calcinosis.
- Raynaud's phenomenon.
- Esophageal dysmotility.
- Sclerodactyly.
- Telangiectasia.
Associated pathology
- Scleroderma panniculitis.
- Digit ischemia - may require finger amputation.