Difference between revisions of "Case 14"
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Low magnification. H&E stain.
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===Provided clinical history=== | ===Provided clinical history=== | ||
61 year old man, diarrhea + hematochezia x 5 months. | 61 year old man, diarrhea + hematochezia x 5 months. | ||
===Site=== | ===Site=== | ||
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===Primary image=== | ===Primary image=== | ||
[[Image:Mantle_cell_lymphoma_-_low_mag.jpg |500px|link=|center|]] | [[Image:Mantle_cell_lymphoma_-_low_mag.jpg|500px|link=|center|]] | ||
<center>Low magnification. [[H&E stain]].</center> | <center>Low magnification. [[H&E stain]].</center> | ||
{{hidden|Intermediate magnification|[[Image:Mantle_cell_lymphoma_-_intermed_mag.jpg |500px|link=|center|]] | {{hidden|Intermediate magnification|[[Image:Mantle_cell_lymphoma_-_intermed_mag.jpg|500px|link=|center|]] | ||
<center>Intermediate magnification. [[H&E stain]].</center>}} | <center>Intermediate magnification. [[H&E stain]].</center>}} | ||
===Differential diagnosis=== | ===Differential diagnosis=== | ||
{{hidden|Differential diagnosis|<center>[[MALT lymphoma]], [[mantle cell lymphoma]]</center>}} | {{hidden|Differential diagnosis|<center>[[ileal nodular lymphoid hyperplasia]], [[MALT lymphoma]], [[mantle cell lymphoma]]</center>}} | ||
===Additional tests=== | ===Additional tests=== | ||
====More history==== | ====More history==== | ||
{{hidden|More history|<center> </center>}} | {{hidden|More history|<center>diffuse erythema on endoscopy, focal erosions, nodularity in ileum</center>}} | ||
====Ask a colleague==== | ====Ask a colleague==== | ||
{{hidden|Ask a colleague|<center> </center>}} | {{hidden|Ask a colleague|<center>Too many lymphoid cells!</center>}} | ||
====Stains==== | ====Stains==== | ||
Line 86: | Line 86: | ||
| cd15= | | cd15= | ||
| cd1a= | | cd1a= | ||
| cd20= | | cd20= '''POSITIVE''' | ||
| cd21= | | cd21= | ||
| cd23= | | cd23= '''NEGATIVE''' | ||
| cd3= | | cd3= '''NEGATIVE''' | ||
| cd30= | | cd30= | ||
| cd31= | | cd31= | ||
Line 95: | Line 95: | ||
| cd35= | | cd35= | ||
| cd4= | | cd4= | ||
| cd43= | | cd43= '''POSITIVE''' | ||
| cd45= | | cd45= '''POSITIVE''' | ||
| cd5= | | cd5= '''POSITIVE''' | ||
| cd56= | | cd56= | ||
| cd68= | | cd68= | ||
| cd7= | | cd7= | ||
| cd79a= | | cd79a= '''POSITIVE''' | ||
| cd8= | | cd8= | ||
| cd99= | | cd99= | ||
Line 112: | Line 112: | ||
| cmv= | | cmv= | ||
| cmyc= | | cmyc= | ||
| | | cyclin_d1= [[Image:Mantle cell lymphoma - intermed mag - cyclin D1.jpg|300px|link=|center|Cyclin D1 IHC.]] | ||
| desmin= | | desmin= | ||
| ebv= | | ebv= | ||
Line 140: | Line 140: | ||
| ki67= | | ki67= | ||
| lambda= | | lambda= | ||
| lca= | | lca= '''POSITIVE''' | ||
| leu7= | | leu7= | ||
| lga= | | lga= | ||
Line 185: | Line 185: | ||
| blank=Dr Torres would ask why! | | blank=Dr Torres would ask why! | ||
| t1_13= | | t1_13= | ||
| t11_14= | | t11_14= '''PRESENT''' | ||
| t11_22dsrct= | | t11_22dsrct= | ||
| t11_22ews= | | t11_22ews= | ||
Line 204: | Line 204: | ||
| tx_18= | | tx_18= | ||
}} | }} | ||
===Diagnosis=== | ===Diagnosis=== | ||
{{hidden|Diagnosis|<center> </center>}} | {{hidden|Diagnosis|<center>[[Mantle cell lymphoma]]</center>}} | ||
<Br> | |||
===Other cases=== | |||
{{Cases navigation|state=collapsed}} | |||
__NOTOC__ | __NOTOC__ | ||
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[[Category:Cases]] | [[Category:Cases]] | ||
[[Category:Cases in gastrointestinal pathology]] | |||
[[Category:Cases in molecular pathology]] | |||
[[Category:Cases difficulty 4]] | |||
[[Category:Cases in gastrointestinal pathology - senior]] | |||
[[Category:Cases in molecular pathology - senior]] |
Latest revision as of 05:35, 2 February 2015
Provided clinical history
61 year old man, diarrhea + hematochezia x 5 months.
Site
Primary image
Intermediate magnification
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Differential diagnosis
Differential diagnosis
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Additional tests
More history
More history
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Ask a colleague
Ask a colleague
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Stains
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IHC
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Chromosomal translocations
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Diagnosis
Diagnosis
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