Difference between revisions of "Herpes esophagitis"

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{{ Infobox diagnosis
| Name      = {{PAGENAME}}
| Image      = Herpes_esophagitis_-_very_high_mag.jpg
| Width      =
| Caption    = Herpes esophagitis
| Synonyms  =
| Micro      = nuclear moulding, multinucleation, margination of chromatin
| Subtypes  =
| LMDDx      =
| Stains    =
| IHC        = HSV-1 +ve
| EM        =
| Molecular  =
| IF        =
| Gross      =
| Grossing  =
| Staging    =
| Site      = [[esophagus]]
| Assdx      =
| Syndromes  =
| Clinicalhx = usually immune deficient
| Signs      =
| Symptoms  =
| Prevalence = rare
| Bloodwork  =
| Rads      =
| Endoscopy  = punched-out ulcers with brown/red edge
| Prognosis  =
| Other      =
| ClinDDx    =
| Tx        =
}}
'''Herpes esophagitis''' is an inflammation of the [[esophagus]] due to [[herpes simplex virus]].
'''Herpes esophagitis''' is an inflammation of the [[esophagus]] due to [[herpes simplex virus]].


==General==
==General==
*Usually immunodeficient.<ref name=pmid23082710>{{Cite journal  | last1 = Monsanto | first1 = P. | last2 = Almeida | first2 = N. | last3 = Cipriano | first3 = MA. | last4 = Gouveia | first4 = H. | last5 = Sofia | first5 = C. | title = Concomitant herpetic and eosinophilic esophagitis--a causality dilemma. | journal = Acta Gastroenterol Belg | volume = 75 | issue = 3 | pages = 361-3 | month = Sep | year = 2012 | doi =  | PMID = 23082710 }}</ref>
Etiology:
Etiology:
*[[Herpes simplex virus]].
*[[Herpes simplex virus]].
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</gallery>


====IHC====
==IHC==
*HSV-1 +ve.<ref name=pmid20616659>{{Cite journal  | last1 = Canalejo Castrillero | first1 = E. | last2 = García Durán | first2 = F. | last3 = Cabello | first3 = N. | last4 = García Martínez | first4 = J. | title = Herpes esophagitis in healthy adults and adolescents: report of 3 cases and review of the literature. | journal = Medicine (Baltimore) | volume = 89 | issue = 4 | pages = 204-10 | month = Jul | year = 2010 | doi = 10.1097/MD.0b013e3181e949ed | PMID = 20616659 }}</ref>
*HSV-1 +ve.<ref name=pmid20616659>{{Cite journal  | last1 = Canalejo Castrillero | first1 = E. | last2 = García Durán | first2 = F. | last3 = Cabello | first3 = N. | last4 = García Martínez | first4 = J. | title = Herpes esophagitis in healthy adults and adolescents: report of 3 cases and review of the literature. | journal = Medicine (Baltimore) | volume = 89 | issue = 4 | pages = 204-10 | month = Jul | year = 2010 | doi = 10.1097/MD.0b013e3181e949ed | PMID = 20616659 }}</ref>
**Occasionally HSV-2 +ve.
**Occasionally HSV-2 +ve.

Latest revision as of 21:28, 6 March 2025

Herpes esophagitis
Diagnosis in short

Herpes esophagitis

LM nuclear moulding, multinucleation, margination of chromatin
IHC HSV-1 +ve
Site esophagus

Clinical history usually immune deficient
Prevalence rare
Endoscopy punched-out ulcers with brown/red edge

Herpes esophagitis is an inflammation of the esophagus due to herpes simplex virus.

General

  • Usually immunodeficient.[1]

Etiology:

Gross/endoscopic

Features:

  • Ulcers with a "punched-out" appearance with a brown/red edge.

Images

www:

Microscopic

Features (3 Ms):

  • Moulding.
  • Multinucleation.
  • Margination of chromatin.

Images

IHC

  • HSV-1 +ve.[2]
    • Occasionally HSV-2 +ve.

See also

References

  1. Monsanto, P.; Almeida, N.; Cipriano, MA.; Gouveia, H.; Sofia, C. (Sep 2012). "Concomitant herpetic and eosinophilic esophagitis--a causality dilemma.". Acta Gastroenterol Belg 75 (3): 361-3. PMID 23082710.
  2. Canalejo Castrillero, E.; García Durán, F.; Cabello, N.; García Martínez, J. (Jul 2010). "Herpes esophagitis in healthy adults and adolescents: report of 3 cases and review of the literature.". Medicine (Baltimore) 89 (4): 204-10. doi:10.1097/MD.0b013e3181e949ed. PMID 20616659.