Foreskin: Difference between revisions
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The [[foreskin]] is a common [[ditzel]]. | |||
==General== | |||
Indications: | |||
*[[Phimosis]]. | |||
Main considerations: | |||
*[[Squamous cell carcinoma]]. | |||
*[[Lichen sclerosus]], [[AKA]] ''balanitis xerotica obliterans''. | |||
*[[Lichen planus]]. | |||
*Infection, e.g. [[syphilis]], [[candidiasis]]. | |||
*[[Zoon balanitis]] - abundant [[plasma cell]]s. | |||
Note: | |||
*Malignant and premalignant lesions are uncommon: 21 of 414 cases.<ref>{{cite journal | authors = West DS, Papalas JA, Selim MA, Vollmer RT | title = Dermatopathology of the foreskin: an institutional experience of over 400 cases | journal = J Cutan Pathol | volume = 40 | issue = 1 | pages = 11–8 | date = January 2013 | pmid = 23106553 | doi = 10.1111/cup.12032}}</ref> | |||
==Microscopic== | |||
Features: | |||
*Usu. fibrotic dermis. | |||
*+/-Inflammation. | |||
DDx: | |||
*See ''[[Penis]]. | |||
===Sign out=== | |||
<pre> | |||
Foreskin, Circumcision: | |||
- Benign squamous mucosa within normal limits, consistent with foreskin. | |||
</pre> | |||
<pre> | |||
A. Foreskin, Circumcision: | |||
- Benign squamous mucosa without significant histopathology, consistent with foreskin. | |||
</pre> | |||
<pre> | |||
Foreskin, Circumcision: | |||
- Benign squamous mucosa with mild patchy chronic inflammation at the epidermal-dermal interface. | |||
- NEGATIVE for dysplasia and NEGATIVE for malignancy. | |||
</pre> | |||
<pre> | |||
Foreskin, Circumcision: | |||
- Squamous mucosa with mild-to-moderate acute and chronic | |||
(lymphocytic) lichenoid inflammation. | |||
- NEGATIVE for evidence of lichen sclerosus. | |||
- NEGATIVE for dysplasia and NEGATIVE for malignancy. | |||
Comment: | |||
A PASD stain is NEGATIVE for micro-organisms. | |||
</pre> | |||
====Micro==== | |||
The section shows squamous mucosa with mild basal pigmentation and subepithelial fibrous tissue. The epithelium matures to the surface. Significant inflammation is ABSENT. Atypia is ABSENT. | |||
===Spongiotic dermatitis=== | |||
<pre> | |||
A. Foreskin, Circumcision: | |||
- Skin with chronic mixed interface inflammation (lymphocyte predominant) and spongiosis. | |||
- NEGATIVE for malignancy. | |||
</pre> | |||
==See also== | |||
[[Ditzels]]. | |||
==References== | |||
{{Reflist|1}} | |||
[[Category:Genitourinary pathology]] | |||
Latest revision as of 19:09, 16 October 2026
The foreskin is a common ditzel.
General
Indications:
Main considerations:
- Squamous cell carcinoma.
- Lichen sclerosus, AKA balanitis xerotica obliterans.
- Lichen planus.
- Infection, e.g. syphilis, candidiasis.
- Zoon balanitis - abundant plasma cells.
Note:
- Malignant and premalignant lesions are uncommon: 21 of 414 cases.[1]
Microscopic
Features:
- Usu. fibrotic dermis.
- +/-Inflammation.
DDx:
- See Penis.
Sign out
Foreskin, Circumcision: - Benign squamous mucosa within normal limits, consistent with foreskin.
A. Foreskin, Circumcision: - Benign squamous mucosa without significant histopathology, consistent with foreskin.
Foreskin, Circumcision: - Benign squamous mucosa with mild patchy chronic inflammation at the epidermal-dermal interface. - NEGATIVE for dysplasia and NEGATIVE for malignancy.
Foreskin, Circumcision: - Squamous mucosa with mild-to-moderate acute and chronic (lymphocytic) lichenoid inflammation. - NEGATIVE for evidence of lichen sclerosus. - NEGATIVE for dysplasia and NEGATIVE for malignancy. Comment: A PASD stain is NEGATIVE for micro-organisms.
Micro
The section shows squamous mucosa with mild basal pigmentation and subepithelial fibrous tissue. The epithelium matures to the surface. Significant inflammation is ABSENT. Atypia is ABSENT.
Spongiotic dermatitis
A. Foreskin, Circumcision: - Skin with chronic mixed interface inflammation (lymphocyte predominant) and spongiosis. - NEGATIVE for malignancy.
See also
References
- ↑ West DS, Papalas JA, Selim MA, Vollmer RT (January 2013). "Dermatopathology of the foreskin: an institutional experience of over 400 cases". J Cutan Pathol 40 (1): 11–8. doi:10.1111/cup.12032. PMID 23106553.