Foreskin

The foreskin is a common ditzel.

General

Indications:

• Phimosis.

Main considerations:

• Squamous cell carcinoma.
• Lichen sclerosus, AKA balanitis xerotica obliterans.
• Lichen planus.
• Infection, e.g. syphilis, candidiasis.
• Zoon balanitis - abundant plasma cells.

Note:

• Malignant and premalignant lesions are uncommon: 21 of 414 cases.

Microscopic

Features:

• Usu. fibrotic dermis.
• +/-Inflammation.

DDx:

• See Penis.

Sign out

Foreskin, Circumcision: 
- Benign squamous mucosa within normal limits, consistent with foreskin. 

A. Foreskin, Circumcision: 
- Benign squamous mucosa without significant histopathology, consistent with foreskin. 

Foreskin, Circumcision: 
- Benign squamous mucosa with mild patchy chronic inflammation at the epidermal-dermal interface.
- NEGATIVE for dysplasia and NEGATIVE for malignancy.

Foreskin, Circumcision: 
- Squamous mucosa with mild-to-moderate acute and chronic 
  (lymphocytic) lichenoid inflammation. 
- NEGATIVE for evidence of lichen sclerosus. 
- NEGATIVE for dysplasia and NEGATIVE for malignancy. 

Comment: 
A PASD stain is NEGATIVE for micro-organisms. 

Micro

The section shows squamous mucosa with mild basal pigmentation and subepithelial fibrous tissue. The epithelium matures to the surface. Significant inflammation is ABSENT. Atypia is ABSENT.

Spongiotic dermatitis

A. Foreskin, Circumcision:
	- Skin with chronic mixed interface inflammation (lymphocyte predominant) and spongiosis.
	- NEGATIVE for malignancy.

See also

Ditzels.