Foreskin

The foreskin is a common ditzel.

General

Indications:

• Phimosis.

Main considerations:

• Squamous cell carcinoma.
• Lichen sclerosus, AKA balanitis xerotica obliterans.
• Lichen planus.
• Infection, e.g. syphilis, candidiasis.
• Zoon balanitis - abundant plasma cells.

Microscopic

Features:

• Usu. fibrotic dermis.
• +/-Inflammation.

DDx:

• See Penis.

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Foreskin, Circumcision: 
- Benign squamous mucosa within normal limits, consistent with foreskin. 

A. Foreskin, Circumcision: 
- Benign squamous mucosa without significant histopathology, consistent with foreskin. 

Foreskin, Circumcision: 
- Benign squamous mucosa with mild patchy chronic inflammation at the epidermal-dermal interface.
- NEGATIVE for dysplasia and NEGATIVE for malignancy.

Foreskin, Circumcision: 
- Squamous mucosa with mild-to-moderate acute and chronic 
  (lymphocytic) lichenoid inflammation. 
- NEGATIVE for evidence of lichen sclerosus. 
- NEGATIVE for dysplasia and NEGATIVE for malignancy. 

Comment: 
A PASD stain is NEGATIVE for micro-organisms. 

Micro

The section shows squamous mucosa with mild basal pigmentation and subepithelial fibrous tissue. The epithelium matures to the surface. Significant inflammation is ABSENT. Atypia is ABSENT.

See also

Ditzels.