Difference between revisions of "Paired box gene 8"
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{{ Infobox immunostain | |||
| Name = {{PAGENAME}} | |||
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| Abbrev = PAX8 | |||
| Synonyms = | |||
| Similar = | |||
| Clones = | |||
| Use = RCC versus other, gynecologic tract malignancy versus other | |||
| Subspecial = [[gynecologic pathology]], [[genitourinary pathology]] | |||
| Pattern = | |||
| Positive = [[renal cell carcinoma]]s, [[renal oncocytoma]], thyroid tumours, [[serous carcinoma]], [[endometrial carcinoma]]s | |||
| Negative = | |||
| Other = | |||
}} | |||
'''Paired box gene 8''', commonly known by the abbreviation '''PAX8''', is a commonly used [[immunostain]] in [[gynecologic pathology]] and [[genitourinary pathology]]. | '''Paired box gene 8''', commonly known by the abbreviation '''PAX8''', is a commonly used [[immunostain]] in [[gynecologic pathology]] and [[genitourinary pathology]]. | ||
Revision as of 22:23, 1 August 2016
| Paired box gene 8 | |
|---|---|
| Immunostain in short | |
| Abbreviation | PAX8 |
| Use | RCC versus other, gynecologic tract malignancy versus other |
| Subspeciality | gynecologic pathology, genitourinary pathology |
| Positive | renal cell carcinomas, renal oncocytoma, thyroid tumours, serous carcinoma, endometrial carcinomas |
Paired box gene 8, commonly known by the abbreviation PAX8, is a commonly used immunostain in gynecologic pathology and genitourinary pathology.
Tumours with positive staining
- Thyroid tumours ~ 90%.[1]
- Renal cell carcinomas ~ 90%.[1]
- Renal oncocytomas ~ 80%.[1]
- High-grade ovarian serous carcinomas ~ 99%.[1]
- Nonserous epithelial ovarian neoplasms ~ 70%.[1]
- Endometrial carcinomas ~ 98%.[1]