Difference between revisions of "Myeloproliferative neoplasms"
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'''Myeloproliferative neoplasms''', also '''myeloproliferative disorders''' are a group of indolent hematologic neoplasms. | '''Myeloproliferative neoplasms''', also '''myeloproliferative disorders''', are a group of indolent hematologic neoplasms. | ||
==Grouping== | ==Grouping== |
Revision as of 14:02, 4 May 2011
Myeloproliferative neoplasms, also myeloproliferative disorders, are a group of indolent hematologic neoplasms.
Grouping
They include the following:[1]
- Polycythaemia vera.
- Essential thrombocythaemia.
- Idiopathic myelofibrosis.
Molecular
There is a common JAK2 mutation (Val617Phe) in this group of diseases.[1]
See also
References
- ↑ Jump up to: 1.0 1.1 Baxter EJ, Scott LM, Campbell PJ, et al. (2005). "Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders". Lancet 365 (9464): 1054–61. doi:10.1016/S0140-6736(05)71142-9. PMID 15781101.