Difference between revisions of "Chronic sialadenitis"
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*Infection. | *Infection. | ||
*Autoimmune (e.g. [[Sjögren syndrome]], [[systemic lupus erythematosus]]). | *Autoimmune (e.g. [[Sjögren syndrome]], [[systemic lupus erythematosus]]). | ||
*[[Smoking]].<ref name=pmid2037973>{{cite journal |author=Eliasson L, Heyden G, Landahl S, Steen B |title=Effects of tobacco and diuretics on human palatal salivary glands |journal=J. Oral Pathol. Med. |volume=20 |issue=3 |pages=126–9 |year=1991 |month=March |pmid=2037973 |doi= |url=}}</ref> | |||
*Other. | *Other. | ||
Revision as of 11:58, 2 June 2014
Chronic sialadenitis is a chronic inflammatory process involving a salivary gland.
Chronic sailolithiasis redirects here. Sialadenitis redirects here.
General
- Occasionally associated with malignancy, e.g. adenoid cystic carcinoma.[1]
Etiology:[2]
- Infection.
- Autoimmune (e.g. Sjögren syndrome, systemic lupus erythematosus).
- Smoking.[3]
- Other.
Gross
Features:
- Salivary gland swelling.[1]
Microscopic
Features:
- Non-neoplastic mononuclear inflammatory infiltrate (lymphocytes, plasma cells).
- Fibrosis.
- +/-Calcifications.
Note:
- If the infiltrate is predominantly lymphocytes Sjögren's is a possibility, and reporting a Focus score should be considered.
DDx:
- Lymphoma - especially MALT lymphoma.[4]
Image
Chronic sialadenitis. (WC/Nephron)
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SUBMANDIBULAR GLAND, RIGHT, EXCISION: - CHRONIC SIALOADENITIS. - SIALOLITHIASIS. - TWO BENIGN LYMPH NODES. - NEGATIVE FOR MALIGNANCY.
Micro
The sections show submandibular salivary gland with a mild patchy mixed mononuclear cell infiltrate, fibrosis and a large benign calcification. No zonal necrosis is identified. Significant nuclear atypia is not identified.
See also
References
- ↑ Jump up to: 1.0 1.1 Hasegawa M, Cheng J, Maruyama S, et al. (June 2011). "Complication of adenoid cystic carcinoma and sialolithiasis in the submandibular gland: report of a case and its etiological background". Int J Oral Maxillofac Surg 40 (6): 647–50. doi:10.1016/j.ijom.2010.11.009. PMID 21159490.
- ↑ URL: http://emedicine.medscape.com/article/882358-overviewhttp://emedicine.medscape.com/article/882358-overview. Accessed on: 10 January 2011.
- ↑ Eliasson L, Heyden G, Landahl S, Steen B (March 1991). "Effects of tobacco and diuretics on human palatal salivary glands". J. Oral Pathol. Med. 20 (3): 126–9. PMID 2037973.
- ↑ Beasley, MJ. (Apr 2012). "Lymphoma of the Thyroid and Head and Neck.". Clin Oncol (R Coll Radiol). doi:10.1016/j.clon.2012.02.010. PMID 22475637.