Foreskin: Difference between revisions
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*Infection, e.g. [[syphilis]], [[candidiasis]]. | *Infection, e.g. [[syphilis]], [[candidiasis]]. | ||
*[[Zoon balanitis]] - abundant [[plasma cell]]s. | *[[Zoon balanitis]] - abundant [[plasma cell]]s. | ||
Note: | |||
*Malignant and premalignant lesions are uncommon: 21 of 414 cases.<ref>{{cite journal | authors = West DS, Papalas JA, Selim MA, Vollmer RT | title = Dermatopathology of the foreskin: an institutional experience of over 400 cases | journal = J Cutan Pathol | volume = 40 | issue = 1 | pages = 11–8 | date = January 2013 | pmid = 23106553 | doi = 10.1111/cup.12032}}</ref> | |||
==Microscopic== | ==Microscopic== | ||
Revision as of 18:43, 16 October 2026
The foreskin is a common ditzel.
General
Indications:
Main considerations:
- Squamous cell carcinoma.
- Lichen sclerosus, AKA balanitis xerotica obliterans.
- Lichen planus.
- Infection, e.g. syphilis, candidiasis.
- Zoon balanitis - abundant plasma cells.
Note:
- Malignant and premalignant lesions are uncommon: 21 of 414 cases.[1]
Microscopic
Features:
- Usu. fibrotic dermis.
- +/-Inflammation.
DDx:
- See Penis.
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Foreskin, Circumcision: - Benign squamous mucosa within normal limits, consistent with foreskin.
A. Foreskin, Circumcision: - Benign squamous mucosa without significant histopathology, consistent with foreskin.
Foreskin, Circumcision: - Benign squamous mucosa with mild patchy chronic inflammation at the epidermal-dermal interface. - NEGATIVE for dysplasia and NEGATIVE for malignancy.
Foreskin, Circumcision: - Squamous mucosa with mild-to-moderate acute and chronic (lymphocytic) lichenoid inflammation. - NEGATIVE for evidence of lichen sclerosus. - NEGATIVE for dysplasia and NEGATIVE for malignancy. Comment: A PASD stain is NEGATIVE for micro-organisms.
Micro
The section shows squamous mucosa with mild basal pigmentation and subepithelial fibrous tissue. The epithelium matures to the surface. Significant inflammation is ABSENT. Atypia is ABSENT.
See also
References
- ↑ West DS, Papalas JA, Selim MA, Vollmer RT (January 2013). "Dermatopathology of the foreskin: an institutional experience of over 400 cases". J Cutan Pathol 40 (1): 11–8. doi:10.1111/cup.12032. PMID 23106553.