Pigmented spindle cell nevus

Pigmented spindle cell nevus, also pigmented spindle cell nevus of Reed, is an uncommon benign melanocytic lesion.

General

• Uncommon.
• Women in teens & 20s.

Gross

• Location: shoulder, pelvic girdle region.

Microscopic

Features:

• Nests of heavily pigmented spindle cells at dermal-epidermal junction - key feature.
  • Nevoid cells in epidermis & dermis - form "basket weave" pattern
• Well-circumscribed lesion.

Notes:

• No epithelioid nevus cells.

DDx:

• Spitz nevus.
• Malignant melanoma.

Images

• Pigmented spindle cell nevus - low mag.jpg

  PSCN - low mag. (WC)

• Pigmented spindle cell nevus - 2 - intermed mag.jpg

  PSCN - intermed. mag. (WC)

• Pigmented spindle cell nevus - 2 - high mag.jpg

  PSCN - high mag. (WC)

www:

• Reed nevus - collection (histopathology-india.net).

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SKIN LESION, RIGHT POSTERIOR NECK, EXCISION:
- PIGMENTED SPINDLE CELL NEVUS OF REED.
-- COMPLETELY EXCISED (CLEARANCE ~ 1 MM).

Micro

The sections show spindled pigmented melanocytes in nests confined to the epidermis. The lesion is symmetrical in its architecture and pigment distribution. There is no pagetoid spread of melanocytes in the epidermis. No significant nuclear atypia is identified. No mitotic activity is appreciated. Melanophages are present in the superficial dermis. The lesion is completely excised in the plane of section.

See also

• Melanocytic lesions.
• Spitz nevus.
• Malignant melanoma.